4'-Fluoro-4-[4-[alpha-hydroxy-alpha-(p-chlorophenyl)benzyl]piperidino]butyrophenone hydrochloride

Base Information

• Chemical Name: 4'-Fluoro-4-[4-[alpha-hydroxy-alpha-(p-chlorophenyl)benzyl]piperidino]butyrophenone hydrochloride
• CAS No.: 57257-41-7
• Molecular Formula: C28H30Cl2FNO2
• Molecular Weight: 502.4477
• DSSTox Substance ID: DTXSID70972745

Synonyms:SCHEMBL11833469;DTXSID70972745;ITNIXNNCCRHPRB-UHFFFAOYSA-N;4'-fluoro-4-[4-[alpha-hydroxy-alpha-(p-chlorophenyl)benzyl]piperidino]butyrophenone hydrochloride;4-{4-[(4-Chlorophenyl)(hydroxy)phenylmethyl]piperidin-1-yl}-1-(4-fluorophenyl)butan-1-one--hydrogen chloride (1/1)

Chemical Property of 4'-Fluoro-4-[4-[alpha-hydroxy-alpha-(p-chlorophenyl)benzyl]piperidino]butyrophenone hydrochloride

Chemical Property:

• Vapor Pressure: 3.42E-16mmHg at 25°C
• Boiling Point: 619.2°C at 760 mmHg
• Flash Point: 328.3°C
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 8
• Exact Mass: 501.1637627
• Heavy Atom Count: 34
• Complexity: 603

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1CN(CCC1C(C2=CC=CC=C2)(C3=CC=C(C=C3)Cl)O)CCCC(=O)C4=CC=C(C=C4)F.Cl

Technology Process of 4'-Fluoro-4-[4-[alpha-hydroxy-alpha-(p-chlorophenyl)benzyl]piperidino]butyrophenone hydrochloride

There total 2 articles about 4'-Fluoro-4-[4-[alpha-hydroxy-alpha-(p-chlorophenyl)benzyl]piperidino]butyrophenone hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

4-<(4-chlorophenyl)phenylhydroxymethyl>piperidine (3811-54-9,149050-85-1,149050-86-2) + 4-(4-fluorophenyl)-4-oxo-n-butyl chloride (3874-54-2,41167-07-1) → 4'-fluoro-4-[4-[α-hydroxy-α-(p-chlorophenyl)benzyl]piperidino]butyrophenone hydrochloride (57257-41-7)

Guidance literature:

With hydrogenchloride; potassium hydrogencarbonate; In toluene; for 60h; Heating;

Reference yield:

ethereal HCl + 4-<(4-chlorophenyl)phenylhydroxymethyl>piperidine (3811-54-9,149050-85-1,149050-86-2) + 4-(4-fluorophenyl)-4-oxo-n-butyl chloride (3874-54-2,41167-07-1) → 4'-fluoro-4-[4-[α-hydroxy-α-(p-chlorophenyl)benzyl]piperidino]butyrophenone hydrochloride (57257-41-7)

Guidance literature:

With potassium iodide; sodium hydrogencarbonate; In toluene;

upstream raw materials:

4-<(4-chlorophenyl)phenylhydroxymethyl>piperidine

4-(4-fluorophenyl)-4-oxo-n-butyl chloride

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 57257-41-7 4-[(4-chlorophenyl)(hydroxy)phenylmethyl]-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidinium chloride

Send

Send

Metric Ton KG G Pound L ML

Send

Send