5-deoxy-5-fluoroinositol

Base Information

• Chemical Name: 5-deoxy-5-fluoroinositol
• CAS No.: 114716-83-5
• Molecular Formula: C6H11 F O5
• Molecular Weight: 182.149
• Mol file: 114716-83-5.mol

Synonyms:5-Deoxy-5-fluoro-myo-inositol

Chemical Property of 5-deoxy-5-fluoroinositol

Chemical Property:

• Vapor Pressure: 8.12E-05mmHg at 25°C
• Boiling Point: 304.7°Cat760mmHg
• Flash Point: 138.1°C
• PSA: 101.15000
• Density: 1.71g/cm³
• LogP: -2.85740

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-deoxy-5-fluoroinositol

There total 13 articles about 5-deoxy-5-fluoroinositol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(3aα,4α,5β,6α,7β,7aα)-6-fluorohexahydro-2,2-dimethylbenzo-1,3(2H)-dioxol-4,5,7-triol (130633-23-7) → (1α,2α,3α,4β,5α,6β)-6-fluoro-1,2,3,4,5-cyclohexanepentol (85716-59-2,114716-79-9,114716-82-4,114716-83-5,116049-87-7,120444-24-8,120444-25-9,130697-82-4,131435-07-9,135212-48-5,136315-50-9)

Guidance literature:

With trifluoroacetic acid; for 4h; Ambient temperature;

Reference yield: 97.0%

DL-1,2,3,4-Tetra-O-acetyl-5-deoxy-5-fluoro-myo-inositol (142544-26-1) → 5-deoxy-5-fluoro-myo-inositol (114716-83-5)

Guidance literature:

With sodium methylate; In methanol; for 2h;

Reference yield: 97.0%

(3aS,4R,5S,6R,7R,7aS)-6-fluoro-2,2-dimethyl-perhydrobenzo[d][1,3]dioxol-4,5,7-triol → 5-deoxy-5-fluoro-myo-inositol (114716-83-5)

Guidance literature:

With hydrogenchloride; In water; for 2h; Ambient temperature;

DOI:10.1016/S0040-4020(97)90392-6

upstream raw materials:

(3aα,4α,5β,6α,7β,7aα)-6-fluorohexahydro-2,2-dimethylbenzo-1,3(2H)-dioxol-4,5,7-triol

(3aα,4β,5α,6β,7α,7aα)-6,7-bis(benzyloxy)-5-fluorohexahydro-2,2-dimethylbenzo-1,3(2H)-dioxol-4-ol

(3aα,4α,5β,6β,7β,7aα)-4,5-bis(benzyloxy)-6,7-epoxyhexahydro-2,2-dimethylbenzo-1,3-dioxole

DL-1,2,3,4-Tetra-O-acetyl-5-deoxy-5-fluoro-myo-inositol

Downstream raw materials:

((R)-1-Phenyl-ethyl)-carbamic acid (1R,3R,5S,6R,7R,8R,9R)-8-(tert-butyl-dimethyl-silanyloxy)-9-fluoro-2,4,10-trioxa-tricyclo[3.3.1.1^3,7]dec-6-yl ester

1,2,3,4,6-penta-O-acetyl-5-deoxy-5-fluoro-myo-inositol