3-Ethyl-3-methylcyclobutanecarboxylic acid

Base Information

• Chemical Name: 3-Ethyl-3-methylcyclobutanecarboxylic acid
• CAS No.: 66016-23-7
• Molecular Formula: C8H14O2
• Molecular Weight: 142.2
• Hs Code.: 2916209090
• Mol file: 66016-23-7.mol

Synonyms:3-Ethyl-3-methyl-cyclobutanecarboxylic acid;CYCLOBUTANECARBOXYLIC ACID,3-ETHYL-3-METHYL;

Chemical Property of 3-Ethyl-3-methylcyclobutanecarboxylic acid

Chemical Property:

• Vapor Pressure: 0.0341mmHg at 25°C
• Boiling Point: 224.1°C at 760 mmHg
• Flash Point: 105.8°C
• PSA: 37.30000
• Density: 1.021g/cm³
• LogP: 1.89730

Purity/Quality:

Cyclobutanecarboxylicacid,3-ethyl-3-methyl- ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Ethyl-3-methylcyclobutanecarboxylic acid

There total 4 articles about 3-Ethyl-3-methylcyclobutanecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

diethyl 2-ethyl-2-methylmalonate (2049-70-9) → 3-Methyl-3-ethylcyclobutan-1-carbonsaeure (66016-23-7)

Guidance literature:

Multi-step reaction with 4 steps

1: LiAlH₄ / diethyl ether / 3 h / Heating

2: MeI, P(OPh)3 / Heating

4: 200 - 210 °C

With triphenyl phosphite; lithium aluminium tetrahydride; methyl iodide; In diethyl ether;

Reference yield:

3-Methyl-3-ethyl-cyclobutan-1.1-dicarbonsaeure → 3-Methyl-3-ethylcyclobutan-1-carbonsaeure (66016-23-7)

Guidance literature:

at 200 - 210 ℃;

Reference yield:

2-ethyl-2-methyl-1,3-propanediol (77-84-9) → 3-Methyl-3-ethylcyclobutan-1-carbonsaeure (66016-23-7)

Guidance literature:

Multi-step reaction with 3 steps

1: MeI, P(OPh)3 / Heating

3: 200 - 210 °C

With triphenyl phosphite; methyl iodide;

upstream raw materials:

2-ethyl-2-methyl-1,3-propanediol

diethyl 2-ethyl-2-methylmalonate

Refernces