1-Hydroxy-3-(4-methylphenyl)urea

Base Information

Chemical Name:1-Hydroxy-3-(4-methylphenyl)urea
CAS No.:53731-86-5
Molecular Formula:C8H10N2O2
Molecular Weight:166.18
Hs Code.:
NSC Number:125196
DSSTox Substance ID:DTXSID00298667
Nikkaji Number:J1.785.827K
Wikidata:Q82040619

Synonyms:53731-86-5;1-hydroxy-3-(4-methylphenyl)urea;NSC125196;SCHEMBL6790850;DTXSID00298667;AKOS024381711;NSC-125196

Suppliers and Price of 1-Hydroxy-3-(4-methylphenyl)urea

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 8 raw suppliers

Chemical Property of 1-Hydroxy-3-(4-methylphenyl)urea

Chemical Property:

Density:1.292g/cm³
XLogP3:0.8
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:166.074227566
Heavy Atom Count:12
Complexity:153

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)NC(=O)NO

Technology Process of 1-Hydroxy-3-(4-methylphenyl)urea

There total 4 articles about 1-Hydroxy-3-(4-methylphenyl)urea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 51457-92-2
N-(benzyloxy)-N'-(p-methylphenyl)urea

: 53731-86-5
N-hydroxy-N’-(p-methylphenyl)urea

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; at 20 ℃; for 3h;
DOI:10.1248/cpb.50.1280

Reference yield:

: 106-49-0,12221-03-3
p-toluidine

: 53731-86-5
N-hydroxy-N’-(p-methylphenyl)urea

Guidance literature:: Multi-step reaction with 3 steps

1: aq. Na₂CO₃ / CH₂Cl₂ / 1.5 h / 20 °C

2: 1488 mg / methanol; CH₂Cl₂; H₂O / 15 h

3: 760.7 mg / H₂ / 10 percent Pd/C / methanol / 3 h / 20 °C

With hydrogen; sodium carbonate; palladium on activated charcoal; In methanol; dichloromethane; water;
DOI:10.1248/cpb.50.1280

Reference yield:

: 622-58-2,374675-64-6
p-Tolylisocyanate

: 53731-86-5
N-hydroxy-N’-(p-methylphenyl)urea

Guidance literature:: Multi-step reaction with 2 steps

1: 1488 mg / methanol; CH₂Cl₂; H₂O / 15 h

2: 760.7 mg / H₂ / 10 percent Pd/C / methanol / 3 h / 20 °C

With hydrogen; palladium on activated charcoal; In methanol; dichloromethane; water;
DOI:10.1248/cpb.50.1280