Actinocylbis(threonyl-d-valyl-4'-oxoproline Methyl Ester

Base Information

Chemical Name:Actinocylbis(threonyl-d-valyl-4'-oxoproline Methyl Ester
CAS No.:66682-49-3
Molecular Formula:C46H58N8O16
Molecular Weight:978.9967
Hs Code.:

Synonyms:Actinocylbis(threonyl-d-valyl-4'-oxoproline Methyl Ester;66682-49-3;L-Proline, 1-(N-(N-((2-amino-9-(((2-hydroxy-1-(((1-((2-(methoxycarbonyl)-4-oxo-1-pyrrolidinyl)carbonyl)-2-methylpropyl)amino)carbonyl)propyl)amino)carbonyl)-4,6-dimethyl-3-oxo-3H-phenoxazin-1-yl)carbonyl)-L-threonyl)-D-valyl)-4-oxo-, methyl ester, stereoisomer

Suppliers and Price of Actinocylbis(threonyl-d-valyl-4'-oxoproline Methyl Ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Actinocylbis(threonyl-d-valyl-4'-oxoproline Methyl Ester

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:1140.3°C at 760 mmHg
Flash Point:643.4°C
Density:1.51g/cm³
XLogP3:0.3
Hydrogen Bond Donor Count:7
Hydrogen Bond Acceptor Count:18
Rotatable Bond Count:18
Exact Mass:978.39707779
Heavy Atom Count:70
Complexity:2310

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C2C(=C(C=C1)C(=O)NC(C(C)O)C(=O)NC(C(C)C)C(=O)N3CC(=O)CC3C(=O)OC)N=C4C(=C(C(=O)C(=C4O2)C)N)C(=O)NC(C(C)O)C(=O)NC(C(C)C)C(=O)N5CCC(=O)C5C(=O)OC

Technology Process of Actinocylbis(threonyl-d-valyl-4'-oxoproline Methyl Ester

There total 3 articles about Actinocylbis(threonyl-d-valyl-4'-oxoproline Methyl Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 16217-15-5
1-benzyloxycarbonyl-4-oxo-L-proline methyl ester

: 66682-49-3
N,N'-(2-amino-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarbonyl)-bis-(L_s-threonyl->D-valyl->4-oxo-L-proline) dimethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: (i) TsOH, (ii) H₂, Pd-C

2: Et₃N, DDc

3: (i) H₂, Pd-C, (ii) aq. K₃

With triethylamine; 2`,3`-dideoxycytidine;
DOI:10.1021/jm00205a004

Reference yield:

: 66682-58-4
1,4-dioxa-7-azaspiro<4.4>-nonane-8(S)-carboxylic acid methyl ester

: 66682-49-3
N,N'-(2-amino-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarbonyl)-bis-(L_s-threonyl->D-valyl->4-oxo-L-proline) dimethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: Et₃N, DDc

2: (i) H₂, Pd-C, (ii) aq. K₃

With triethylamine; 2`,3`-dideoxycytidine;
DOI:10.1021/jm00205a004