(1,4-Bis(3,4,5-trimethoxybenzoyl)-2-piperazinyl)methyl 2-ethylbutanoate

Base Information

Chemical Name:(1,4-Bis(3,4,5-trimethoxybenzoyl)-2-piperazinyl)methyl 2-ethylbutanoate
CAS No.:129229-96-5
Molecular Formula:C₃₁H₄₂N₂O₁₀
Molecular Weight:602.682
Hs Code.:
DSSTox Substance ID:DTXSID00926337
ChEMBL ID:CHEMBL6270

Synonyms:(1,4-Bis(3,4,5-trimethoxybenzoyl)-2-piperazinyl)methyl 2-ethylbutanoate;129229-96-5;CHEMBL6270;N,N'-Di-(3',4',5'-trimethoxybenzoyl)-2-(2'-ethyl)butanoyloxymethylpiperazine;Butanoic acid, 2-ethyl-, (1,4-bis(3,4,5-trimethoxybenzoyl)-2-piperazinyl)methyl ester;[1,4-bis(3,4,5-trimethoxybenzoyl)piperazin-2-yl]methyl 2-ethylbutanoate;SCHEMBL10469597;DTXSID00926337;BDBM50046963;LS-46283;2-Ethyl-butyric acid 1,4-bis-(3,4,5-trimethoxy-benzoyl)-piperazin-2-ylmethyl ester

Suppliers and Price of (1,4-Bis(3,4,5-trimethoxybenzoyl)-2-piperazinyl)methyl 2-ethylbutanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of (1,4-Bis(3,4,5-trimethoxybenzoyl)-2-piperazinyl)methyl 2-ethylbutanoate

Chemical Property:

Vapor Pressure:6.28E-22mmHg at 25°C
Boiling Point:742.7°C at 760 mmHg
Flash Point:403°C
Density:1.18g/cm³
XLogP3:3.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:14
Exact Mass:602.28394554
Heavy Atom Count:43
Complexity:874

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(CC)C(=O)OCC1CN(CCN1C(=O)C2=CC(=C(C(=C2)OC)OC)OC)C(=O)C3=CC(=C(C(=C3)OC)OC)OC

Technology Process of (1,4-Bis(3,4,5-trimethoxybenzoyl)-2-piperazinyl)methyl 2-ethylbutanoate

There total 9 articles about (1,4-Bis(3,4,5-trimethoxybenzoyl)-2-piperazinyl)methyl 2-ethylbutanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 4521-61-3
3,4,5-Trimethoxybenzoyl chloride

: 2-Ethyl-butyric acid piperazin-2-ylmethyl ester; hydrochloride

: 129229-96-5
N,N'-di-(3',4',5'-trimethoxybenzoyl)-2-(2'-ethyl)-butanoyloxymethyl piperazine

Guidance literature:: With triethylamine; In benzene; Ambient temperature;
DOI:10.1021/jm00060a006

Reference yield:

: 2736-40-5
chlorure d'acide ethyl-2 butyrique

: 129229-96-5
N,N'-di-(3',4',5'-trimethoxybenzoyl)-2-(2'-ethyl)-butanoyloxymethyl piperazine

Guidance literature:: Multi-step reaction with 3 steps

1: 70 percent / Et₃N / benzene / Ambient temperature

2: H₂, conc. HCl / 10percent Pd/C / ethanol / 40 °C / 2068.6 Torr

3: 72 percent / Et₃N / benzene / Ambient temperature

With hydrogenchloride; hydrogen; triethylamine; palladium on activated charcoal; In ethanol; benzene;
DOI:10.1021/jm00060a006

Reference yield:

: 148227-89-8,148228-28-8,148228-31-3
2-Ethyl-butyric acid 1,4-dibenzyl-piperazin-2-ylmethyl ester

: 129229-96-5
N,N'-di-(3',4',5'-trimethoxybenzoyl)-2-(2'-ethyl)-butanoyloxymethyl piperazine

Guidance literature:: Multi-step reaction with 2 steps

1: H₂, conc. HCl / 10percent Pd/C / ethanol / 40 °C / 2068.6 Torr

2: 72 percent / Et₃N / benzene / Ambient temperature

With hydrogenchloride; hydrogen; triethylamine; palladium on activated charcoal; In ethanol; benzene;
DOI:10.1021/jm00060a006