N-(2-aminophenyl)-N-(4-methylphenyl)amine hydrochloride

Base Information

• Chemical Name: N-(2-aminophenyl)-N-(4-methylphenyl)amine hydrochloride
• CAS No.: 91806-09-6
• Molecular Formula: C13H14N2
• Molecular Weight: 198.268
• Hs Code.: 2921590090
• European Community (EC) Number: 856-759-0
• DSSTox Substance ID: DTXSID70554404
• Mol file: 91806-09-6.mol

Synonyms:91806-09-6;N-(2-aminophenyl)-N-(4-methylphenyl)amine hydrochloride;384371-27-1;N1-(4-methylphenyl)benzene-1,2-diamine hydrochloride;2-N-(4-methylphenyl)benzene-1,2-diamine;hydrochloride;N-(2-AMINOPHENYL)-N-(4-METHYLPHENYL)AMINEHYDROCHLORIDE;1-N-(4-methylphenyl)benzene-1,2-diamine hydrochloride;DTXSID70554404;HMS1402J17;AKOS005110109;MS-2807;EN300-02818;N~1~-(4-Methylphenyl)benzene-1,2-diamine--hydrogen chloride (1/1)

Chemical Property of N-(2-aminophenyl)-N-(4-methylphenyl)amine hydrochloride

Chemical Property:

• Vapor Pressure: 4.06E-05mmHg at 25°C
• Boiling Point: 351.6°C at 760 mmHg
• Flash Point: 195.6°C
• PSA: 38.05000
• Density: 1.139g/cm³
• LogP: 4.77700
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 234.0923762
• Heavy Atom Count: 16
• Complexity: 185

Purity/Quality:

1-N-(4-methylphenyl)benzene-1,2-diamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)NC2=CC=CC=C2N.Cl

Technology Process of N-(2-aminophenyl)-N-(4-methylphenyl)amine hydrochloride

There total 18 articles about N-(2-aminophenyl)-N-(4-methylphenyl)amine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

para-bromotoluene (106-38-7) + 1,2-diamino-benzene (95-54-5) → N1-(p-tolyl)benzene-1,2-diamine (91806-09-6)

Guidance literature:

With nickel(II) bromide trihydrate; N,N-dimethyl-cyclohexanamine; C₇₀H₇₅BN₂; In 1,2-dimethoxyethane; N,N-dimethyl-formamide; at 80 ℃; for 36h; Inert atmosphere; Irradiation;

Reference yield: 84.0%

5-chloro-N-(4-methylphenyl)-2-nitrosoaniline (947590-21-8) → N1-(p-tolyl)benzene-1,2-diamine (91806-09-6)

Guidance literature:

With hydrogen; triethylamine; palladium on activated charcoal; In methanol; at 20 ℃; for 0.5h;

DOI:10.1055/s-2007-982534

Reference yield: 80.0%

(2-nitrophenyl)-p-tolylamine (52753-44-3) → N1-(p-tolyl)benzene-1,2-diamine (91806-09-6)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In ethanol; at 20 ℃; for 2h; under 2068.65 Torr; Sealed tube;

upstream raw materials:

(2-nitrophenyl)-p-tolylamine

3-amino-4-p-toluidino-benzoic acid

2-allylamino-4'-methyldiphenylamine

5-chloro-N-(4-methylphenyl)-2-nitrosoaniline

Downstream raw materials:

1-(4-methylphenyl)-1H-benzimidazole

1-(4-methylphenyl)-1H-benzo[d][1,2,3]triazole

2-allylamino-4'-methyldiphenylamine

1-(p-tolyl)-1,3-dihydro-2H-benzo[d]imidazol-2-one