2-Amino-3-piperidin-1-ylpropanoic acid

Base Information

• Chemical Name: 2-Amino-3-piperidin-1-ylpropanoic acid
• CAS No.: 4724-46-3
• Molecular Formula: C8H16N2O2
• Molecular Weight: 172.2248
• NSC Number: 192628
• DSSTox Substance ID: DTXSID20307543
• Nikkaji Number: J920.887I
• Mol file: 4724-46-3.mol

Synonyms:4724-46-3;2-amino-3-piperidin-1-ylpropanoic acid;2-amino-3-(piperidin-1-yl)propanoic acid;(R)-2-Amino-3-(piperidin-1-yl)propanoic acid;(S)-2-Amino-3-(piperidin-1-yl)propanoic acid;911633-41-5;NSC192628;3-piperidin-1-ylalanine;3-(1-piperidinyl)-D-alanine;3-(1-piperidinyl)-L-alanine;SCHEMBL1176730;DTXSID20307543;AKOS011014350;NSC-192628;2-amino-3-(piperidin-1-yl)propanoicacid;EN300-149445

Chemical Property of 2-Amino-3-piperidin-1-ylpropanoic acid

Chemical Property:

• Vapor Pressure: 8.93E-05mmHg at 25°C
• Boiling Point: 316.2°C at 760 mmHg
• Flash Point: 145°C
• Density: 1.146g/cm³
• XLogP3: -2.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 172.121177757
• Heavy Atom Count: 12
• Complexity: 155

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCN(CC1)CC(C(=O)O)N

Technology Process of 2-Amino-3-piperidin-1-ylpropanoic acid

There total 3 articles about 2-Amino-3-piperidin-1-ylpropanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

acetylamino-piperidinomethyl-malonic acid diethyl ester (7460-52-8) → β-piperidinoalanine (4724-46-3)

Guidance literature:

acetylamino-piperidinomethyl-malonic acid diethyl ester; With hydrogenchloride; water; Heating / reflux;

With sodium hydroxide; In water; pH=11;

Reference yield:

formylamino-piperidinomethyl-malonic acid diethyl ester (202979-89-3) → β-piperidinoalanine (4724-46-3)

Guidance literature:

With hydrogenchloride;

Reference yield:

piperidine (110-89-4) → β-piperidinoalanine (4724-46-3)

Guidance literature:

Multi-step reaction with 2 steps

2: aqueous hydrochloric acid

With hydrogenchloride;

upstream raw materials:

formylamino-piperidinomethyl-malonic acid diethyl ester

piperidine

acetylamino-piperidinomethyl-malonic acid diethyl ester

Downstream raw materials:

α-(benzoylamino)-1-piperidinepropanoic acid

C₃₃H₄₆N₆O₆

C₁₅H₂₁N₃O₂S

2-{3-(2,4-dichlorophenyl)ureido}-3-(piperidin-1-yl)propanoic acid