Ethyl 4-(3-hydroxyphenyl)-2-methyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate

Base Information

Chemical Name:Ethyl 4-(3-hydroxyphenyl)-2-methyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate
CAS No.:5405-37-8
Molecular Formula:C31H52 O2
Molecular Weight:456.753
Hs Code.:
DSSTox Substance ID:DTXSID50385834
Mol file:5405-37-8.mol

Synonyms:5405-37-8;ethyl 4-(3-hydroxyphenyl)-2-methyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate;ethyl 4-(3-hydroxyphenyl)-2-methyl-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carboxylate;SR-01000208076;Oprea1_512362;Oprea1_650294;SCHEMBL3328920;DTXSID50385834;BADMFIGZWYVFLU-UHFFFAOYSA-N;STK363192;AKOS000572231;AKOS021985560;AG-690/10379063;SR-01000208076-1;SR-01000208076-2;SR-01000208076-3;ethyl 4-(3-hydroxyphenyl)-2-methyl-5-oxo-1,4,5,6,7,8-hexahydro-3-quinolinecarboxylate

Suppliers and Price of Ethyl 4-(3-hydroxyphenyl)-2-methyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of Ethyl 4-(3-hydroxyphenyl)-2-methyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate

Chemical Property:

Vapor Pressure:1.23E-11mmHg at 25°C
Boiling Point:524.9°Cat760mmHg
Flash Point:271.3°C
PSA：75.63000
Density:1.27g/cm³
LogP:3.25200
XLogP3:2.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:327.14705815
Heavy Atom Count:24
Complexity:605

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=C(NC2=C(C1C3=CC(=CC=C3)O)C(=O)CCC2)C

Technology Process of Ethyl 4-(3-hydroxyphenyl)-2-methyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate

There total 10 articles about Ethyl 4-(3-hydroxyphenyl)-2-methyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 20817-72-5,55722-32-2,83603-21-8
(22E)-stigmasta-4,22-dien-3-one

: 5405-37-8,13010-52-1,55529-48-1,62841-18-3,120709-26-4
5β-stigmasten-(22t)-yl-(3α)-acetate

Guidance literature:: Multi-step reaction with 2 steps

1: ethyl acetate; platinum / Hydrogenation

2: sodium; propanol-⁽¹⁾ / Kochen des (ueber die Verbindung mit Digitonin isolierten) Reaktionsprodukts mit Acetanhydrid

With propan-1-ol; sodium; ethyl acetate; platinum;
DOI:10.1021/ja01160a056

Reference yield:

: 4736-55-4
5β-stigmast-22t-en-3-one

: 5405-37-8,13010-52-1,55529-48-1,62841-18-3,120709-26-4
5β-stigmasten-(22t)-yl-(3α)-acetate

Guidance literature:: Multi-step reaction with 2 steps

1: sodium; propanol-⁽¹⁾ / Erwaermen auf dem Dampfbad, Reinigung ueber das O-Acetyl-Derivat

With propan-1-ol; sodium;
DOI:10.1021/ja01160a056

Reference yield:

: 4736-55-4
5β-stigmast-22t-en-3-one

: 5405-37-8,13010-52-1,55529-48-1,62841-18-3,120709-26-4
5β-stigmasten-(22t)-yl-(3α)-acetate

: 62841-18-3
5β-stigmasten-(22t)-yl-(3β)-acetate

Guidance literature:: With propan-1-ol; sodium; Kochen des (ueber die Verbindung mit Digitonin isolierten) Reaktionsprodukts mit Acetanhydrid;
DOI:10.1021/ja01160a056