1-Methyl-4-phenylpiperidin-4-amine

Base Information

Chemical Name:1-Methyl-4-phenylpiperidin-4-amine
CAS No.:100316-65-2
Molecular Formula:C12H18N2
Molecular Weight:190.288
Hs Code.:
DSSTox Substance ID:DTXSID40550938
Wikidata:Q82430428
Mol file:100316-65-2.mol

Synonyms:1-METHYL-4-PHENYLPIPERIDIN-4-AMINE;100316-65-2;4-Piperidinamine, 1-methyl-4-phenyl-;1-methyl-4-phenyl-4-piperidinamine;SCHEMBL56772;DTXSID40550938;SB42884;EN300-1703680;AE-641/00356053

Suppliers and Price of 1-Methyl-4-phenylpiperidin-4-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 1-Methyl-4-phenylpiperidin-4-amine

Chemical Property:

XLogP3:1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:190.146998583
Heavy Atom Count:14
Complexity:177

Purity/Quality:: 95%+ or 98%+ ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CCC(CC1)(C2=CC=CC=C2)N

Technology Process of 1-Methyl-4-phenylpiperidin-4-amine

There total 4 articles about 1-Methyl-4-phenylpiperidin-4-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4972-68-3
1-methyl-4-phenyl-piperidin-4-ol

: 28289-54-5
1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine

: 100316-65-2
4-amino-1-methyl-4-phenylpiperidine

Guidance literature:: With potassium hydroxide; sodium cyanide; Yield given. Multistep reaction. Yields of byproduct given; 1.) acetic acid / H₂SO₄; 2.) ethanol, reflux, 3 h;

Reference yield:

: 201055-91-6
N-(1-methyl-4-phenyl-[4]piperidyl)-acetamide

: 100316-65-2
4-amino-1-methyl-4-phenylpiperidine

Guidance literature:: With diphenylsilane; titanium(IV)isopropoxide; In tetrahydrofuran; at 20 ℃;
DOI:10.1016/j.bmcl.2008.09.042

Reference yield:

: 4275-17-6
bis(2-bromoethyl)-N-(methyl)amine

: 100316-65-2
4-amino-1-methyl-4-phenylpiperidine

Guidance literature:: Multi-step reaction with 3 steps

1: potassium-t-butoxide / dimethyl sulfoxide / 17.5 h / 0 - 20 °C

2: potassium carbonate; dihydrogen peroxide / dimethyl sulfoxide / 2.5 h / 60 °C

3: sodium hydroxide; sodium chlorine monoxide / acetonitrile / 11 h / 0 - 20 °C / 760.05 Torr / pH 13

With sodium chlorine monoxide; potassium-t-butoxide; dihydrogen peroxide; potassium carbonate; sodium hydroxide; In dimethyl sulfoxide; acetonitrile;