(5R)-5-Hydroxy-1,7-diphenyl-3-heptanone

Base Information

• Chemical Name: (5R)-5-Hydroxy-1,7-diphenyl-3-heptanone
• CAS No.: 100761-20-4
• Molecular Formula: C19H22O2
• Molecular Weight: 282.37700
• Mol file: 100761-20-4.mol

Synonyms:5-epidihydroyashabushiketol;5-hydroxy-1,7-diphenyl-3-heptanone;(R)-5-Hydroxy-1,7-diphenyl-heptan-3-one;

Chemical Property of (5R)-5-Hydroxy-1,7-diphenyl-3-heptanone

Chemical Property:

• PSA: 37.30000
• LogP: 3.57210

Purity/Quality:

≥98% ^*data from raw suppliers

(R)-5-Hydroxy-1,7-diphenyl-3-heptanone ≥98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (5R)-5-Hydroxy-1,7-diphenyl-3-heptanone

There total 31 articles about (5R)-5-Hydroxy-1,7-diphenyl-3-heptanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

C19H19NO → 5-hydroxy-1,7-diphenylheptan-3-one (24192-01-6,93603-99-7,100761-20-4,55836-43-6)

Guidance literature:

With 5% Pd(II)/C(eggshell); hydrogen;

DOI:10.1016/j.tetasy.2011.04.014

Reference yield: 99.0%

1-(2-Phenethyl-[1,3]dioxolan-2-yl)-4-phenyl-butan-2-ol (93559-15-0) → 5-hydroxy-1,7-diphenylheptan-3-one (24192-01-6,93603-99-7,100761-20-4,55836-43-6)

Guidance literature:

With hydrogen fluoride;

Reference yield: 96.0%

C19H21ClO2 → (S)-1,7-diphenyl-5-hydroxy-3-heptanone (24192-01-6,55836-43-6,93603-99-7,100761-20-4)

Guidance literature:

With 2,2'-azobis(isobutyronitrile); tris-(trimethylsilyl)silane; In toluene; at 110 ℃; for 18h; Inert atmosphere; Sealed tube;

DOI:10.1039/c3ob27462d

upstream raw materials:

3-phenyl-propionaldehyde

4-Phenyl-2-butanone

1,7-diphenylheptane-3,5-diol

1-(2-Phenethyl-[1,3]dioxolan-2-yl)-4-phenyl-butan-2-ol

Downstream raw materials:

5-methoxy-1,7-diphenyl-3-heptanone

4-(dimethyl-λ4-sulfanylidene)-1,7-diphenylheptane-3,5-dione

Benzoic acid (S)-3-oxo-1-phenethyl-5-phenyl-pentyl ester

1,7-bisphenylheptane-3,5-dione