2-Hydroxy-1-(1-hydroxycyclohexyl)ethanone

Base Information

Chemical Name:2-Hydroxy-1-(1-hydroxycyclohexyl)ethanone
CAS No.:100849-70-5
Molecular Formula:C8H14O3
Molecular Weight:158.197
Hs Code.:
DSSTox Substance ID:DTXSID20541945
Nikkaji Number:J2.031.875I
Wikidata:Q82418426
Mol file:100849-70-5.mol

Synonyms:2-hydroxy-1-(1-hydroxycyclohexyl)ethanone;100849-70-5;DTXSID20541945;2-hydroxy-1-(1-hydroxy-cyclohexyl)-ethanone;2-Hydroxy-1-(1-hydroxycyclohexyl)ethan-1-one

Suppliers and Price of 2-Hydroxy-1-(1-hydroxycyclohexyl)ethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-Hydroxy-1-(1-hydroxycyclohexyl)ethanone

Chemical Property:

XLogP3:0.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:158.094294304
Heavy Atom Count:11
Complexity:147

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCC(CC1)(C(=O)CO)O

Technology Process of 2-Hydroxy-1-(1-hydroxycyclohexyl)ethanone

There total 21 articles about 2-Hydroxy-1-(1-hydroxycyclohexyl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 13957-27-2
1-(2-bromoethynyl)cyclohexanol

: 65-85-0,8013-63-6
benzoic acid

: 100849-70-5
2-hydroxy-1-(1-hydroxycyclohexyl)ethan-1-one

: Benzoic acid 2-(1-hydroxy-cyclohexyl)-2-oxo-ethyl ester

Guidance literature:: With water; caesium carbonate; In N,N-dimethyl-formamide; at 50 - 55 ℃; for 4h;
DOI:10.1002/ejoc.201901226

Reference yield: 71.0%

: 408328-76-7
1-(2-acetoxyacetyl)cyclohexyl acetate

: 100849-70-5
2-hydroxy-1-(1-hydroxycyclohexyl)ethan-1-one

Guidance literature:: With scandium tris(trifluoromethanesulfonate); In ethanol; water; at 20 ℃; for 24h; under 760.051 Torr; Inert atmosphere;
DOI:10.1002/adsc.201900314

Reference yield:

: 78-27-3
1-Ethynylcyclohexan-1-ol

: 591-50-4
iodobenzene

: 100849-70-5
2-hydroxy-1-(1-hydroxycyclohexyl)ethan-1-one

Guidance literature:: With bis-(trifluoroacetoxy)-iodo-benzene; silica gel; Yield given. Multistep reaction; 1) CHCl₃/CH₃CN/H₂O, 80 deg C, 10 h, 2) ethyl acetate;
DOI:10.1016/S0040-4039(00)89264-3