(1R,4R)-5-(PHENYLMETHYL)-2,5-DIAZABICYCLO[2.2.1]HEPTANE DIHYDROBROMIDE

Base Information

Chemical Name:(1R,4R)-5-(PHENYLMETHYL)-2,5-DIAZABICYCLO[2.2.1]HEPTANE DIHYDROBROMIDE
CAS No.:100944-15-8
Molecular Formula:2BrH*C₁₂H₁₆N₂
Molecular Weight:350.096
Hs Code.:
Mol file:100944-15-8.mol

Synonyms:(1S,4S)-2-benzyl-2,5-diazabicyclo[2.2.1]heptane bis hydrobromide salt;(1S,4S)-N-benzyl-2,5-diaza-bicyclo[2.2.1]heptane dihydrobromide;(1S,4S)-2-(phenylmethyl)-2,5-diazabicyclo[2.2.1]heptane dihydrobromide;(1S,4S)-2-Benzyl-2,5-diazabicyclo(2.2.1)heptane dihydrobromide;(1S,4S)-2-benzyl-2,5-diazabicyclo[2.2.1]heptane bis-hydrobromide;(1S,4S)-2-benzyl-2,5-diazabicyclo[2.2.1]heptane dihydrobromide;

Suppliers and Price of (1R,4R)-5-(PHENYLMETHYL)-2,5-DIAZABICYCLO[2.2.1]HEPTANE DIHYDROBROMIDE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of (1R,4R)-5-(PHENYLMETHYL)-2,5-DIAZABICYCLO[2.2.1]HEPTANE DIHYDROBROMIDE

Chemical Property:

PSA：15.27000
LogP:2.45750

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (1R,4R)-5-(PHENYLMETHYL)-2,5-DIAZABICYCLO[2.2.1]HEPTANE DIHYDROBROMIDE

There total 3 articles about (1R,4R)-5-(PHENYLMETHYL)-2,5-DIAZABICYCLO[2.2.1]HEPTANE DIHYDROBROMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 5234-72-0,59436-75-8
(1S,4S)-5-Benzyl-2-tosyl-2,5-diazabicyclo<2.2.1>heptane

: 100944-15-8,134003-82-0,116258-17-4
(1S,4S)-2-Benzyl-2,5-diazabicyclo<2.2.1>heptane dihydrobromide

Guidance literature:: With hydrogen bromide; at 110 ℃; for 0.5h; microwave irradiation;
DOI:10.1002/ejoc.200700785

Reference yield:

: 51-35-4,30724-02-8
4R-4-hydroxyproline

: 100944-15-8,134003-82-0,116258-17-4
(1S,4S)-2-Benzyl-2,5-diazabicyclo<2.2.1>heptane dihydrobromide

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium carbonate / water

1.3: 20 h

2.1: toluene / Reflux

3.1: hydrogen bromide

With hydrogen bromide; sodium carbonate; In water; toluene;
DOI:10.1080/14756366.2017.1363197

Reference yield:

: 5234-75-3
(2S,4R)-1-(4-tolylsulfonyl)-4-<(4-tolylsulfonyl)oxy>-2-<<(4-tolylsulfonyl)oxy>methyl>pyrrolidine

: 100944-15-8,134003-82-0,116258-17-4
(1S,4S)-2-Benzyl-2,5-diazabicyclo<2.2.1>heptane dihydrobromide

Guidance literature:: Multi-step reaction with 2 steps

1: toluene / Reflux

2: hydrogen bromide

With hydrogen bromide; In toluene;
DOI:10.1080/14756366.2017.1363197