2H-1,2,4-Benzothiadiazine-3-propanoic acid, 5,7-dichloro-, 1,1-dioxide

Base Information

Chemical Name:2H-1,2,4-Benzothiadiazine-3-propanoic acid, 5,7-dichloro-, 1,1-dioxide
CAS No.:101063-93-8
Molecular Formula:C10H8Cl2N2O4S
Molecular Weight:323.15300
Hs Code.:
DSSTox Substance ID:DTXSID80541966
Nikkaji Number:J347.880G
Wikidata:Q82418456
Mol file:101063-93-8.mol

Synonyms:101063-93-8;2H-1,2,4-Benzothiadiazine-3-propanoic acid, 5,7-dichloro-, 1,1-dioxide;3-(5,7-dichloro-1,1-dioxo-4H-1lambda6,2,4-benzothiadiazin-3-yl)propanoic acid;DTXSID80541966;3-(5,7-Dichloro-1,1-dioxido-2H-benzo[e][1,2,4]thiadiazin-3-yl)propanoic acid;3-(5,7-Dichloro-1,1-dioxo-1,4-dihydro-1lambda~6~,2,4-benzothiadiazin-3-yl)propanoic acid

Suppliers and Price of 2H-1,2,4-Benzothiadiazine-3-propanoic acid, 5,7-dichloro-, 1,1-dioxide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of 2H-1,2,4-Benzothiadiazine-3-propanoic acid, 5,7-dichloro-, 1,1-dioxide

Chemical Property:

PSA：104.21000
LogP:3.02530
XLogP3:1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:321.9581833
Heavy Atom Count:19
Complexity:502

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C=C(C2=C1S(=O)(=O)N=C(N2)CCC(=O)O)Cl)Cl

Technology Process of 2H-1,2,4-Benzothiadiazine-3-propanoic acid, 5,7-dichloro-, 1,1-dioxide

There total 2 articles about 2H-1,2,4-Benzothiadiazine-3-propanoic acid, 5,7-dichloro-, 1,1-dioxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: N-(2,4-Dichloro-6-sulfamoyl-phenyl)-succinamic acid methyl ester

: 101063-93-8
3-(5,7-Dichloro-1,1-dioxo-1,4-dihydro-1λ⁶-benzo[1,2,4]thiadiazin-3-yl)-propionic acid

Guidance literature:: With sodium hydroxide; at 20 - 25 ℃; for 24h;
DOI:10.1002/ardp.19853181008

Reference yield:

: 59018-66-5
2-amino-3,5-diclorobenzenesolfonamide

: 101063-93-8
3-(5,7-Dichloro-1,1-dioxo-1,4-dihydro-1λ⁶-benzo[1,2,4]thiadiazin-3-yl)-propionic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / N,N-dimethyl-acetamide / 20 - 25 °C

2: 96 percent / 0.5percent aq. NaOH / 24 h / 20 - 25 °C

With sodium hydroxide; In N,N-dimethyl acetamide;
DOI:10.1002/ardp.19853181008