2-(3-Carboxyacetoxyphenyl)imidazo(2,1-b)benzothiazole

Base Information

Chemical Name:2-(3-Carboxyacetoxyphenyl)imidazo(2,1-b)benzothiazole
CAS No.:87545-58-2
Molecular Formula:C18H12N2O4S
Molecular Weight:352.3639
Hs Code.:
DSSTox Substance ID:DTXSID001007627
Nikkaji Number:J357.103C
Wikidata:Q83003746

Synonyms:2-(3-carboxyacetoxyphenyl)imidazo(2,1-b)benzothiazole;YM 13650;YM-13650

Suppliers and Price of 2-(3-Carboxyacetoxyphenyl)imidazo(2,1-b)benzothiazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-(3-Carboxyacetoxyphenyl)imidazo(2,1-b)benzothiazole

Chemical Property:

PSA：109.14000
Density:1.48g/cm³
LogP:3.59610
XLogP3:4.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:352.05177804
Heavy Atom Count:25
Complexity:531

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)N3C=C(N=C3S2)C4=CC(=CC=C4)OC(=O)CC(=O)O

Technology Process of 2-(3-Carboxyacetoxyphenyl)imidazo(2,1-b)benzothiazole

There total 3 articles about 2-(3-Carboxyacetoxyphenyl)imidazo(2,1-b)benzothiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 51932-41-3
malonic acid monochloride

: 79889-39-7
2-(m-hydroxyphenyl)imidazo<2,1-b>benzothiazole

: 87545-58-2
2-(m-carboxyacetoxyphenyl)imidazo<2,1-b>benzothiazole

Guidance literature:: With hydrogenchloride; potassium fluoride; sodium hydrogencarbonate; In tetrahydrofuran; N-methyl-acetamide; ethyl acetate;

Reference yield:

: 87545-59-3
2-imidazo<2,1-b>benzothiazole

: 87545-58-2
2-(m-carboxyacetoxyphenyl)imidazo<2,1-b>benzothiazole

Guidance literature:: With methoxybenzene; trifluoroacetic acid; at 3 - 15 ℃; for 1h; Yield given;
DOI:10.1016/0223-5234(88)90205-X

Reference yield:

: 79889-39-7
2-(m-hydroxyphenyl)imidazo<2,1-b>benzothiazole

: 87545-58-2
2-(m-carboxyacetoxyphenyl)imidazo<2,1-b>benzothiazole

Guidance literature:: Multi-step reaction with 2 steps

1: DCC / pyridine / 3 h / 20 - 25 °C

2: anizole, TFA / 1 h / 3 - 15 °C

With methoxybenzene; dicyclohexyl-carbodiimide; trifluoroacetic acid; In pyridine;
DOI:10.1016/0223-5234(88)90205-X