2-(1-Naphthyl)-2-butanol

Base Information

• Chemical Name: 2-(1-Naphthyl)-2-butanol
• CAS No.: 102238-70-0
• Molecular Formula: C14H16O
• European Community (EC) Number: 651-845-2
• Nikkaji Number: J2.155.788I
• Mol file: 102238-70-0.mol

Synonyms:2-(1-Naphthyl)-2-butanol;102238-70-0;2-(Naphthalen-1-yl)butan-2-ol;2-naphthalen-1-ylbutan-2-ol;starbld0045797;SCHEMBL2482276;AKOS012081988

Chemical Property of 2-(1-Naphthyl)-2-butanol

Chemical Property:

• XLogP3: 3.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 200.120115130
• Heavy Atom Count: 15
• Complexity: 213

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC(C)(C1=CC=CC2=CC=CC=C21)O

Technology Process of 2-(1-Naphthyl)-2-butanol

There total 2 articles about 2-(1-Naphthyl)-2-butanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

1'-naphthacetophenone (941-98-0) + ethylmagnesium bromide (925-90-6) + methyllithium (917-54-4) → 2-(naphthalen-1-yl)propan-2-ol (6301-54-8) + 2-(1-naphthyl)-2-butanol (102238-70-0)

Guidance literature:

ethylmagnesium bromide; methyllithium; In tetrahydrofuran; diethyl ether; at -78 ℃; for 1h;

1'-naphthacetophenone; In tetrahydrofuran; diethyl ether; at -78 ℃; for 5h;

DOI:10.1021/ol047685i

Reference yield: 9.0%

1'-naphthacetophenone (941-98-0) + ethylmagnesium bromide (925-90-6) → 1-(1-naphthyl)ethanol (57605-95-5,1517-72-2) + 2-(1-naphthyl)-2-butanol (102238-70-0)

Guidance literature:

In tetrahydrofuran; at -78 ℃; for 5h;

DOI:10.1021/ol047685i

upstream raw materials:

1'-naphthacetophenone

ethylmagnesium bromide

methyllithium