1,3,8-Triazaspiro[4.5]decan-4-one, 1-(4-methylphenyl)-

Base Information

Chemical Name:1,3,8-Triazaspiro[4.5]decan-4-one, 1-(4-methylphenyl)-
CAS No.:1023-87-6
Molecular Formula:C14H19N3O
Molecular Weight:245.32000
Hs Code.:
DSSTox Substance ID:DTXSID10442154
Wikidata:Q82259274
Mol file:1023-87-6.mol

Synonyms:1023-87-6;1-(4-methylphenyl)-1,3,8-triazaspiro[4.5]decan-4-one;1-(p-Tolyl)-1,3,8-triazaspiro[4.5]decan-4-one;1,3,8-Triazaspiro[4.5]decan-4-one, 1-(4-methylphenyl)-;SCHEMBL5556794;DTXSID10442154;TQP0840

Suppliers and Price of 1,3,8-Triazaspiro[4.5]decan-4-one, 1-(4-methylphenyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 1,3,8-Triazaspiro[4.5]decan-4-one, 1-(4-methylphenyl)-

Chemical Property:

PSA：44.37000
LogP:1.73350
XLogP3:1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:245.152812238
Heavy Atom Count:18
Complexity:317

Purity/Quality:: 98%,99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)N2CNC(=O)C23CCNCC3

Technology Process of 1,3,8-Triazaspiro[4.5]decan-4-one, 1-(4-methylphenyl)-

There total 1 articles about 1,3,8-Triazaspiro[4.5]decan-4-one, 1-(4-methylphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1023-87-6
1-(4-methylphenyl)-1,3,8-triazaspiro<4.5>decan-4-one

Guidance literature:: aus 1-Oxo-8-benzyl-4-p-tolyl-2,4,8-triazaspiro<4.5>decan u. H2 (Pd/C);

Reference yield: 47.0%

: 80119-31-9
N-(3-chloropropyl)-4-fluoro-N-(4-fluorophenyl)benzenamine

: 1023-87-6
1-(4-methylphenyl)-1,3,8-triazaspiro<4.5>decan-4-one

: 97861-02-4
8-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-1-p-tolyl-1,3,8-triaza-spiro[4.5]decan-4-one

Guidance literature:: With potassium carbonate; sodium iodide; In various solvent(s); for 16h; Heating;
DOI:10.1021/jm00150a011

Reference yield:

: 1444-65-1
(RS)-2-phenylcyclohexanone

: 1023-87-6
1-(4-methylphenyl)-1,3,8-triazaspiro<4.5>decan-4-one

: (rac,cis)-8-(2-phenyl-cyclohexyl)-1-p-tolyl-1,3,8-triaza-spiro[4.5]decan-4-one

Guidance literature:: (RS)-2-phenylcyclohexanone; 1-(4-methylphenyl)-1,3,8-triazaspiro<4.5>decan-4-one; With titanium(IV) isopropylate; at 105 ℃;

With sodium tetrahydroborate; In ethanol; at 20 ℃;
DOI:10.1016/j.bmcl.2005.09.075