1-(3,4-Dimethoxyphenyl)-2-(2-dipropylaminoethyl)-3-methyl-1,2,3,4-tetrahydro-beta-carboline

Base Information

Chemical Name:1-(3,4-Dimethoxyphenyl)-2-(2-dipropylaminoethyl)-3-methyl-1,2,3,4-tetrahydro-beta-carboline
CAS No.:106287-99-4
Molecular Formula:C₂₈H₃₉N₃O₂
Molecular Weight:449.637
Hs Code.:
DSSTox Substance ID:DTXSID50909973

Synonyms:BRN 5779821;1-(3,4-Dimethoxyphenyl)-2-(2-dipropylaminoethyl)-3-methyl-1,2,3,4-tetrahydro-beta-carboline;106287-99-4;2H-Pyrido(3,4-b)indole-2-ethanamine, 1,3,4,9-tetrahydro-1-(3,4-dimethoxyphenyl)-N,N-dipropyl-3-dimethyl-;DTXSID50909973;C28H39N3O2;LS-133522;N-{2-[1-(3,4-Dimethoxyphenyl)-3-methyl-1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indol-2-yl]ethyl}-N-propylpropan-1-amine

Suppliers and Price of 1-(3,4-Dimethoxyphenyl)-2-(2-dipropylaminoethyl)-3-methyl-1,2,3,4-tetrahydro-beta-carboline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 1-(3,4-Dimethoxyphenyl)-2-(2-dipropylaminoethyl)-3-methyl-1,2,3,4-tetrahydro-beta-carboline

Chemical Property:

Vapor Pressure:5.09E-13mmHg at 25°C
Boiling Point:570.3°C at 760 mmHg
Flash Point:298.7°C
Density:1.081g/cm³
XLogP3:5.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:10
Exact Mass:449.30422750
Heavy Atom Count:33
Complexity:584

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCN(CCC)CCN1C(CC2=C(C1C3=CC(=C(C=C3)OC)OC)NC4=CC=CC=C24)C

Technology Process of 1-(3,4-Dimethoxyphenyl)-2-(2-dipropylaminoethyl)-3-methyl-1,2,3,4-tetrahydro-beta-carboline

There total 4 articles about 1-(3,4-Dimethoxyphenyl)-2-(2-dipropylaminoethyl)-3-methyl-1,2,3,4-tetrahydro-beta-carboline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

: 106288-06-6
2-[1-(3,4-Dimethoxy-phenyl)-3-methyl-1,3,4,9-tetrahydro-β-carbolin-2-yl]-N,N-dipropyl-acetamide

: 106287-99-4
{2-[1-(3,4-Dimethoxy-phenyl)-3-methyl-1,3,4,9-tetrahydro-β-carbolin-2-yl]-ethyl}-dipropyl-amine

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; diethyl ether; for 18h; Heating;
DOI:10.1007/BF00763777

Reference yield:

: 299-26-3,304-54-1
1-(1H-indol-3-yl)propan-2-amine

: 106287-99-4
{2-[1-(3,4-Dimethoxy-phenyl)-3-methyl-1,3,4,9-tetrahydro-β-carbolin-2-yl]-ethyl}-dipropyl-amine

Guidance literature:: Multi-step reaction with 3 steps

1: 56 percent / 2 N aq. H₂SO₄ / 0.5 h / 100 °C

2: 75 percent / Na₂CO₃ / acetone / 12 h / Heating

3: 56 percent / LiAlH₄ / tetrahydrofuran; diethyl ether / 18 h / Heating

With lithium aluminium tetrahydride; sulfuric acid; sodium carbonate; In tetrahydrofuran; diethyl ether; acetone;
DOI:10.1007/BF00763777

Reference yield:

: 120-14-9
3,4-dimethoxy-benzaldehyde

: 106287-99-4
{2-[1-(3,4-Dimethoxy-phenyl)-3-methyl-1,3,4,9-tetrahydro-β-carbolin-2-yl]-ethyl}-dipropyl-amine

Guidance literature:: Multi-step reaction with 3 steps

1: 56 percent / 2 N aq. H₂SO₄ / 0.5 h / 100 °C

2: 75 percent / Na₂CO₃ / acetone / 12 h / Heating

3: 56 percent / LiAlH₄ / tetrahydrofuran; diethyl ether / 18 h / Heating

With lithium aluminium tetrahydride; sulfuric acid; sodium carbonate; In tetrahydrofuran; diethyl ether; acetone;
DOI:10.1007/BF00763777