3-(2-carboxyindol-3-yl)propionic acid

Base Information

Chemical Name:3-(2-carboxyindol-3-yl)propionic acid
CAS No.:31529-28-9
Molecular Formula:C12H11 N O4
Molecular Weight:233.224
Hs Code.:2933990090
Mol file:31529-28-9.mol

Synonyms:3-Indolepropionicacid, 2-carboxy- (3CI); Indole-3-propionic acid, 2-carboxy- (6CI,8CI)

Suppliers and Price of 3-(2-carboxyindol-3-yl)propionic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
3-(2-Carboxyethyl)-1H-indole-2-carboxylic acid
500mg
$ 189.00

Crysdot
3-(2-Carboxyethyl)-1H-indole-2-carboxylicacid 97%
5g
$ 594.00

Chemenu
3-(2-Carboxyethyl)-1H-indole-2-carboxylicacid 95%+
5g
$ 561.00

American Custom Chemicals Corporation
3-(2-CARBOXYETHYL)-1H-INDOLE-2-CARBOXYLIC ACID 95.00%
500MG
$ 785.40

AK Scientific
3-(2-Carboxyethyl)-1H-indole-2-carboxylicacid
500mg
$ 305.00

Total 6 raw suppliers

Chemical Property of 3-(2-carboxyindol-3-yl)propionic acid

Chemical Property:

Vapor Pressure:3.4E-12mmHg at 25°C
Boiling Point:533.1°Cat760mmHg
Flash Point:276.2°C
PSA：90.39000
Density:1.472g/cm³
LogP:1.88330

Purity/Quality:

98%min ^*data from raw suppliers

3-(2-Carboxyethyl)-1H-indole-2-carboxylic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-(2-carboxyindol-3-yl)propionic acid

There total 17 articles about 3-(2-carboxyindol-3-yl)propionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: methyl 3-(3-methoxy-3-oxopropyl)-1H-indole-2-carboxylate

: 31529-28-9
3-(2-carboxyethyl)-1H-indole-2-carboxylic acid

Guidance literature:: With potassium hydroxide; In methanol; for 4h; Reflux;
DOI:10.1021/jacs.6b08094

Reference yield: 16.0%

: 63158-53-2
ethyl 3-(3-ethoxy-3-oxopropyl)-1H-indole-2-carboxylate

: 31529-28-9
3-(2-carboxyethyl)-1H-indole-2-carboxylic acid

Guidance literature:: With lithium hydroxide trihydrate; In tetrahydrofuran; water; at 20 ℃; for 24h;
DOI:10.1021/acs.jmedchem.7b01768

Reference yield:

: 611-10-9
2-ethoxycarbonyl-1-cyclopentanone

: 31529-28-9
3-(2-carboxyethyl)-1H-indole-2-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) aq. HCl, sodium nitrite, 2.) sodium acetate / 1.) from 0 deg C to 5 deg C, 2.) water, from 0 deg C to RT, 75 min

2: H₂SO₄ / Heating

3: aq. LiOH / tetrahydrofuran / Ambient temperature

With hydrogenchloride; lithium hydroxide; sulfuric acid; sodium acetate; sodium nitrite; In tetrahydrofuran;
DOI:10.1021/jm00088a014