tert-butyl 4-(bromomethyl)-3-methoxybenzoate

Base Information

• Chemical Name: tert-butyl 4-(bromomethyl)-3-methoxybenzoate
• CAS No.: 104436-91-1
• Molecular Formula: C13H17BrO3
• Molecular Weight: 301.18
• Hs Code.: 2918990090
• Mol file: 104436-91-1.mol

Synonyms:tert-butyl 4-(bromomethyl)-3-methoxybenzoate;RD-07;t-butyl 4-bromomethyl-3-methoxybenzoate;tert-butyl (3-formylbenzyl)carbamate;(3-formyl-benzyl)-carbamic acid tert-butyl ester;t-butyl 3-formylbenzylcarbamate;t-butyl 3-methoxy-4-bromomethylbenzoate;tert-butyl N-(3 formylbenzyl)carbamate;4-tert-butoxycarbonyl-2-methoxybenzyl bromide;t-butyl N-(3-formylbenzyl)carbamate;

Chemical Property of tert-butyl 4-(bromomethyl)-3-methoxybenzoate

Chemical Property:

• PSA: 35.53000
• LogP: 3.54540

Purity/Quality:

tert-butyl4-(bromomethyl)-3-methoxybenzoate 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of tert-butyl 4-(bromomethyl)-3-methoxybenzoate

There total 4 articles about tert-butyl 4-(bromomethyl)-3-methoxybenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

tert-butyl 3-methoxy-4-methylbenzoate (104436-90-0) → t-butyl 4-bromomethyl-3-methoxybenzoate (104436-91-1)

Guidance literature:

With N-Bromosuccinimide; Perbenzoic acid; In tetrachloromethane; for 1h; Heating; Irradiation;

DOI:10.1021/jm00168a036

Reference yield: 95.0%

tert-butyl 3-methoxy-4-methylbenzoate (104436-90-0) → 4-[6-(Cyclopentylmethylcarbamoyl)methyl-3-(2-mor-pholinocarbonyl)ethylindol-1-ylmethyl]-3-methoxy-N-(2-methylphenylsulfonyl)benzamide + t-butyl 4-bromomethyl-3-methoxybenzoate (104436-91-1)

Guidance literature:

With N-Bromosuccinimide; dibenzoyl peroxide; In tetrachloromethane;

Reference yield: 77.0%

→ 6-(2-ethylhexanamido)-3-formylindole (104437-00-5) + t-butyl 4-bromomethyl-3-methoxybenzoate (104436-91-1)

Guidance literature:

upstream raw materials:

tert-butyl 3-methoxy-4-methylbenzoate

3-methoxy-p-toluic acid

Downstream raw materials:

tert-butyl 3-methoxy-4-<(6-nitroindol-1-yl)methyl>benzoate

tert-butyl 4-<<6-(heptafluorobutanamido)indol-1-yl>methyl>-3-methoxybenzoate

4-<<6-(heptafluorobutanamido)indol-1-yl>methyl>-3-methoxybenzoic acid

tert-butyl 4-<(6-aminoindazol-1-yl)methyl>-3-methoxybenzoate