N-(4-chlorophenyl)-3,4-dihydro-2H-quinoline-1-carboxamide

Base Information

Chemical Name:N-(4-chlorophenyl)-3,4-dihydro-2H-quinoline-1-carboxamide
CAS No.:6198-79-4
Molecular Formula:C16H15ClN2O
Molecular Weight:286.7561
Hs Code.:
DSSTox Substance ID:DTXSID60351565
Wikidata:Q82128074

Synonyms:N-(4-chlorophenyl)-3,4-dihydro-2H-quinoline-1-carboxamide;6198-79-4;N-(4-chlorophenyl)-3,4-dihydro-1(2H)-quinolinecarboxamide;N-(4-chlorophenyl)-3,4-dihydroquinoline-1(2H)-carboxamide;CBMicro_002864;ChemDiv1_023246;Oprea1_575303;Oprea1_775688;HMS653A14;DTXSID60351565;SMSF0017114;CCG-18026;STK014642;AKOS000487977;CB04845;BIM-0002816.P001;AN-329/40390917;SR-01000456629;SR-01000456629-1;N-(4-CHLOROPHENYL)-1,2,3,4-TETRAHYDROQUINOLINE-1-CARBOXAMIDE

Suppliers and Price of N-(4-chlorophenyl)-3,4-dihydro-2H-quinoline-1-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 0 raw suppliers

Chemical Property of N-(4-chlorophenyl)-3,4-dihydro-2H-quinoline-1-carboxamide

Chemical Property:

Vapor Pressure:1.11E-09mmHg at 25°C
Boiling Point:488.2°C at 760 mmHg
Flash Point:249°C
Density:1.316g/cm³
XLogP3:3.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:286.0872908
Heavy Atom Count:20
Complexity:341

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2=CC=CC=C2N(C1)C(=O)NC3=CC=C(C=C3)Cl

Technology Process of N-(4-chlorophenyl)-3,4-dihydro-2H-quinoline-1-carboxamide

There total 14 articles about N-(4-chlorophenyl)-3,4-dihydro-2H-quinoline-1-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

: 725232-75-7
methyl 2,3-anhydro-4-O-methanesulfonyl-β-D-ribopyranoside

: 6160-95-8,6198-79-4
methyl 2,3-anhydro-4-azido-4-deoxy-α-L-lyxopyranoside

Guidance literature:: With sodium azide; In N,N-dimethyl-formamide; at 90 - 115 ℃; for 0.75h;
DOI:10.1016/j.tet.2004.04.040

Reference yield: 32.0%

: 863998-31-6
methyl 2,3-anhydro-4-O-methanesulfonyl-α-D-ribopyranoside

: 6198-79-4
methyl 2,3-anhydro-4-azido-4-deoxy-β-L-lyxopyranoside

: methyl 2,4-diazido-2,4-dideoxy-β-L-xylopyranoside

Guidance literature:: With sodium azide; In N,N-dimethyl-formamide; at 95 ℃; for 1h;
DOI:10.1016/j.carres.2005.06.006

Reference yield:

: 3150-13-8
(1R,2R,5R,6R)-2-Methoxy-3,7-dioxa-bicyclo[4.1.0]heptan-5-ol

: 6160-95-8,6198-79-4
methyl 2,3-anhydro-4-azido-4-deoxy-α-L-lyxopyranoside

Guidance literature:: Multi-step reaction with 2 steps

1: 97 percent / Et₃N / CH₂Cl₂ / 0.5 h / -10 °C

2: 56 percent / NaN₃ / dimethylformamide / 0.75 h / 90 - 115 °C

With sodium azide; triethylamine; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/j.tet.2004.04.040