6-Chloro-n4-(4-methylphenyl)pyrimidine-2,4-diamine

Base Information

Chemical Name:6-Chloro-n4-(4-methylphenyl)pyrimidine-2,4-diamine
CAS No.:7249-31-2
Molecular Formula:C₁₁H₁₁ClN₄
Molecular Weight:234.688
Hs Code.:
NSC Number:43274
DSSTox Substance ID:DTXSID90285940
Wikidata:Q82021492

Synonyms:7249-31-2;n-(2-amino-6-chloro-4-pyrimidinyl)-n-(4-methylphenyl)amine;NSC43274;6-chloro-n4-(4-methylphenyl)pyrimidine-2,4-diamine;SCHEMBL3233125;DTXSID90285940;KAUBSLPJWJEOKU-UHFFFAOYSA-N;NSC-43274;STL090049;AKOS003096830;6-chloro-N*4*-p-tolyl-pyrimidine-2,4-diamine;6-Chloro-N4-(p-tolyl)pyrimidine-2,4-diamine;6-chloro-N4-(4methylphenyl)-2,4-pyrimidinediamine;6-chloro-N~4~-(4-methylphenyl)pyrimidine-2,4-diamine;6-CHLORO-N4-(4-METHYLPHENYL)-2,4-PYRIMIDINEDIAMINE

Suppliers and Price of 6-Chloro-n4-(4-methylphenyl)pyrimidine-2,4-diamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 6-Chloro-n4-(4-methylphenyl)pyrimidine-2,4-diamine

Chemical Property:

Vapor Pressure:6.07E-09mmHg at 25°C
Boiling Point:468.3°C at 760 mmHg
Flash Point:237°C
Density:1.361g/cm³
XLogP3:3.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:234.0672241
Heavy Atom Count:16
Complexity:218

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC=C(C=C1)NC2=CC(=NC(=N2)N)Cl

Technology Process of 6-Chloro-n4-(4-methylphenyl)pyrimidine-2,4-diamine

There total 3 articles about 6-Chloro-n4-(4-methylphenyl)pyrimidine-2,4-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.0%

: 33344-18-2
2-Amino-6-p-toluidinopyrimidin-4(3H)-one

: 7249-31-2
2-Amino-4-chloro-6-p-toluidinopyrimidine

Guidance literature:: With trichlorophosphate; at 90 ℃; for 4h;
DOI:10.1002/jhet.5570280611

Reference yield:

: 106-49-0,12221-03-3
p-toluidine

: 7249-31-2
2-Amino-4-chloro-6-p-toluidinopyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: 61 percent / p-toluidine hydrochloride / 0.83 h / 130 - 140 °C

2: 25 percent / POCl₃ / 4 h / 90 °C

With p-toluidine hydrochloride; trichlorophosphate;
DOI:10.1002/jhet.5570280611