2-(2-Methoxyanilino)-4-oxo-4,5-dihydrofuran-3-carboxylic acid

Base Information

Chemical Name:2-(2-Methoxyanilino)-4-oxo-4,5-dihydrofuran-3-carboxylic acid
CAS No.:106212-55-9
Molecular Formula:C₁₂H₁₁NO₅
Molecular Weight:249.223
Hs Code.:
ChEMBL ID:CHEMBL57738
DSSTox Substance ID:DTXSID80547665
Wikidata:Q82426015

Synonyms:106212-55-9;CHEMBL57738;DTXSID80547665;2-(2-Methoxyanilino)-4-oxo-4,5-dihydrofuran-3-carboxylic acid

Suppliers and Price of 2-(2-Methoxyanilino)-4-oxo-4,5-dihydrofuran-3-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(2-Methoxyanilino)-4-oxo-4,5-dihydrofuran-3-carboxylic acid

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:249.06372245
Heavy Atom Count:18
Complexity:390

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=CC=C1NC2=C(C(=O)CO2)C(=O)O

Technology Process of 2-(2-Methoxyanilino)-4-oxo-4,5-dihydrofuran-3-carboxylic acid

There total 3 articles about 2-(2-Methoxyanilino)-4-oxo-4,5-dihydrofuran-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 106212-63-9
N-(2-methoxyphenyl)-2,5-dihydro-2-oxo-4--3-furancarboxamide

: 106212-55-9
4,5-dihydro-2-<(o-methoxyphenyl)amino>-4-oxo-3-furancarboxylic acid

Guidance literature:: With potassium hydroxide; In ethanol; water; for 22h; Heating;
DOI:10.1002/hlca.19880710413

Reference yield:

: 700-87-8
1-Isocyanato-2-methoxy-benzene

: 106212-55-9
4,5-dihydro-2-<(o-methoxyphenyl)amino>-4-oxo-3-furancarboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: Et₃N / ethyl acetate; petroleum ether

2: 8percent aq. Na₂CO₃ / Heating

With sodium carbonate; triethylamine; In ethyl acetate; Petroleum ether;
DOI:10.1021/jm00118a008