N,N-Dimethyl-N'-phenethylformamidine

Base Information

• Chemical Name: N,N-Dimethyl-N'-phenethylformamidine
• CAS No.: 15795-36-5
• Molecular Formula: C11H16 N2
• Molecular Weight: 176.261
• Hs Code.: 2925290090
• Mol file: 15795-36-5.mol

Synonyms:Formamidine,N,N-dimethyl-N'-phenethyl- (6CI,8CI); NSC 100782

Chemical Property of N,N-Dimethyl-N'-phenethylformamidine

Chemical Property:

• Boiling Point: 265oC at 760 mmHg
• Flash Point: 114.1oC
• PSA: 15.60000
• Density: 0.9g/cm3
• LogP: 1.81900

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N,N-Dimethyl-N'-phenethylformamidine

There total 5 articles about N,N-Dimethyl-N'-phenethylformamidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-phenylethylamine hydrochloride (156-28-5) + N,N-dimethyl-formamide dimethyl acetal (4637-24-5) → N,N-dimethyl-N'-phenethyl-formamidine (15795-36-5)

Guidance literature:

for 2h; Reflux;

DOI:10.1039/c2cc38382a

Reference yield: 92.0%

N,N-dimethyl-formamide dimethyl acetal (4637-24-5) + phenethylamine (64-04-0) → N,N-dimethyl-N'-phenethyl-formamidine (15795-36-5)

Guidance literature:

In neat (no solvent); at 80 ℃; Microwave irradiation;

DOI:10.1016/j.tet.2020.131205

Reference yield:

phenethyl azide (6926-44-9) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → N,N-dimethyl-N'-phenethyl-formamidine (15795-36-5)

Guidance literature:

With triphenylphosphine;

DOI:10.1139/v74-326

upstream raw materials:

phenethylamine

N,N-dimethyl-formamide

phenethyl azide

2-phenylethylamine hydrochloride

Downstream raw materials:

C₂₈H₃₄N₄O₆

C₂₁H₂₆N₄O₄

C₉H₁₂N₂O

Refernces

• 1、 Cao, Han,Bie, Fu-sheng,Liu, Xue-jing,Han, Ying,Ma, Jie,Shi, Yi-jun,Yan, Peng,Sun, Chao-yue,Wang, Hai-meng. "Novel synthesis of 1-substituted-4-imidazolecarboxylates via solvent-free cycloaddition reaction between formamidines and isocyanides". . . Retrieved 2020/04/27.