5-Bromo-4-chloro-6-phenylpyrimidin-2-amine

Base Information

Chemical Name:5-Bromo-4-chloro-6-phenylpyrimidin-2-amine
CAS No.:106791-93-9
Molecular Formula:C10H7BrClN3
Molecular Weight:284.543
Hs Code.:
DSSTox Substance ID:DTXSID00559508
Wikidata:Q82442256
Mol file:106791-93-9.mol

Synonyms:5-bromo-4-chloro-6-phenylpyrimidin-2-amine;106791-93-9;SCHEMBL10567530;DTXSID00559508;WPECLXUICXOZRA-UHFFFAOYSA-N;AKOS015957345;5-bromo-4-chloro-6-phenyl-2-pyrimidinamine;CS-0045627;EN300-236620;F2158-1071

Suppliers and Price of 5-Bromo-4-chloro-6-phenylpyrimidin-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
5-Bromo-4-chloro-6-phenylpyrimidin-2-amine 95%+
1g
$ 1177.00

Chemenu
5-Bromo-4-chloro-6-phenylpyrimidin-2-amine 95%+
250mg
$ 522.00

Chemenu
5-Bromo-4-chloro-6-phenylpyrimidin-2-amine 95%+
100mg
$ 353.00

Total 4 raw suppliers

Chemical Property of 5-Bromo-4-chloro-6-phenylpyrimidin-2-amine

Chemical Property:

PSA：52.53000
LogP:3.07180
XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:282.95119
Heavy Atom Count:15
Complexity:211

Purity/Quality:

NLT 98% ^*data from raw suppliers

5-Bromo-4-chloro-6-phenylpyrimidin-2-amine 95%+ ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=C(C(=NC(=N2)N)Cl)Br

Technology Process of 5-Bromo-4-chloro-6-phenylpyrimidin-2-amine

There total 3 articles about 5-Bromo-4-chloro-6-phenylpyrimidin-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.5%

: 36314-97-3
4-chloro-6-phenylpyrimidin-2-amine

: 106791-93-9
2-amino-5-bromo-4-chloro-6-phenylpyrimidine

Guidance literature:: With N-Bromosuccinimide; In acetonitrile; at 80 ℃; for 14h;

Reference yield: 67.0%

: 56741-95-8
bropirimine

: 106791-93-9
2-amino-5-bromo-4-chloro-6-phenylpyrimidine

Guidance literature:: With trichlorophosphate; for 0.75h; Heating;
DOI:10.1016/S0968-0896(00)00017-1

Reference yield:

: 98-80-6
phenylboronic acid

: 106791-93-9
2-amino-5-bromo-4-chloro-6-phenylpyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / 1,4-dioxane; water / 23 h / 20 °C / Inert atmosphere

2: N-Bromosuccinimide / acetonitrile / 14 h / 80 °C

With N-Bromosuccinimide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In 1,4-dioxane; water; acetonitrile;