Methyl 11-methoxy-19-methyl-16,17-didehydro-18-oxayohimban-16-carboxylate

Base Information

• Chemical Name: Methyl 11-methoxy-19-methyl-16,17-didehydro-18-oxayohimban-16-carboxylate
• CAS No.: 14883-83-1
• Molecular Formula: C₂₂H₂₆N₂O₄
• Molecular Weight: 382.459
• NSC Number: 72290
• DSSTox Substance ID: DTXSID80933488
• Wikidata: Q82909306
• Mol file: 14883-83-1.mol

Synonyms:MLS002638438;NSC72290;methyl 11-methoxy-19-methyl-16,17-didehydro-18-oxayohimban-16-carboxylate;NCIOpen2_008687;SCHEMBL15385124;ACon1_001476;DTXSID80933488;NSC-72290;SMR001547918;BRD-A07616163-001-01-4;4H-Indolo(2,4-g)quinolizine-16-carboxylic acid, 4a,5,7,8,13,13B,14,14a-octahydro-11-methoxy-4-methyl-, methyl ester;Oxayohimban-16-carboxylic acid,17-didehydro-11-methoxy-19-methyl-, methyl ester, (19.beta.,20.alpha.)-

Chemical Property of Methyl 11-methoxy-19-methyl-16,17-didehydro-18-oxayohimban-16-carboxylate

Chemical Property:

• Vapor Pressure: 2.83E-12mmHg at 25°C
• Melting Point: 276-8°C
• Boiling Point: 553°C at 760 mmHg
• Flash Point: 288.3°C
• PSA: 63.79000
• Density: 1.3g/cm³
• LogP: 3.12530
• XLogP3: 2.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 3
• Exact Mass: 382.18925731
• Heavy Atom Count: 28
• Complexity: 652

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1C2CN3CCC4=C(C3CC2C(=CO1)C(=O)OC)NC5=C4C=CC(=C5)OC
• Description: This alkaloid is fairly widespread among the members of the Rauwolfia species where it is found mainly in the leaves. It is isomeric with Raumitorine (q.v.) from which it differs only in the position of the methoxyl group. The ultraviolet spectrum in EtOH has three absorption maxima occurring at 229, 265 and 282 mμ.

Technology Process of Methyl 11-methoxy-19-methyl-16,17-didehydro-18-oxayohimban-16-carboxylate

There total 1 articles about Methyl 11-methoxy-19-methyl-16,17-didehydro-18-oxayohimban-16-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ Raunitidin, (+/-)-3-Iso-20-allo-reserpsaeure-lacton (482-94-0,482-95-1,482-96-2,13555-43-6,14883-83-1,36063-55-5,81202-53-1,132016-18-3)

Guidance literature:

(+/-)-2,3-Seco-3-oxo-20-allo-reserpsaeure-lacton, 1.) POCl3, 2.) NaBH4;