3-Benzyl-1-hydroxypyrrolidine-2,5-dione

Base Information

Chemical Name:3-Benzyl-1-hydroxypyrrolidine-2,5-dione
CAS No.:106847-88-5
Molecular Formula:C11H11NO3
Molecular Weight:205.21000
Hs Code.:
DSSTox Substance ID:DTXSID50561757
Mol file:106847-88-5.mol

Synonyms:3-benzyl-1-hydroxypyrrolidine-2,5-dione;106847-88-5;2,5-Pyrrolidinedione, 1-hydroxy-3-(phenylmethyl)-;SCHEMBL8379405;DTXSID50561757

Suppliers and Price of 3-Benzyl-1-hydroxypyrrolidine-2,5-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 3-Benzyl-1-hydroxypyrrolidine-2,5-dione

Chemical Property:

PSA：57.61000
LogP:0.93130
XLogP3:0.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:205.07389321
Heavy Atom Count:15
Complexity:271

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(C(=O)N(C1=O)O)CC2=CC=CC=C2

Technology Process of 3-Benzyl-1-hydroxypyrrolidine-2,5-dione

There total 12 articles about 3-Benzyl-1-hydroxypyrrolidine-2,5-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

: 910581-40-7
2-benzyl-N¹-(prop-2-ynyl)-N⁴-(trityloxy)succinamide

: 910581-48-5
2-benzyl-N⁴-hydroxy-N¹-(prop-2-ynyl)succinamide

: 106847-88-5
3-benzyl-1-hydroxypyrrolidine-2,5-dione

Guidance literature:: With chlorotriisopropylsilane; trifluoroacetic acid; In dichloromethane; for 1h;
DOI:10.1021/ol061431a

Reference yield:

: 106847-89-6
3-benzyl-N-(benzyloxy)succinimide

: 106847-88-5
3-benzyl-1-hydroxypyrrolidine-2,5-dione

Guidance literature:: With hydrogen; palladium on activated charcoal; In tetrahydrofuran; for 3h;
DOI:10.1021/jm00127a034

Reference yield:

: 36092-42-9,884-33-3
2-benzylsuccinic acid

: 106847-88-5
3-benzyl-1-hydroxypyrrolidine-2,5-dione

Guidance literature:: Multi-step reaction with 3 steps

1: acetic anhydride / 1 h / Heating

2: toluene / 0.5 h / Heating

3: H₂ / Pd/C (10percent) / tetrahydrofuran / 3 h

With hydrogen; acetic anhydride; palladium on activated charcoal; In tetrahydrofuran; toluene;
DOI:10.1021/jm00127a034