Pipendoxifene

Base Information

• Chemical Name: Pipendoxifene
• CAS No.: 198480-55-6
• Deprecated CAS: 352233-89-7
• Molecular Formula: C₂₉H₃₂N₂O₃
• Molecular Weight: 456.585
• UNII: TPC5Q8496G
• DSSTox Substance ID: DTXSID40870209
• Nikkaji Number: J1.561.274F
• Wikipedia: Pipendoxifene
• Wikidata: Q27095593
• NCI Thesaurus Code: C1874
• Pharos Ligand ID: 1WFZYY8KCNHU
• Metabolomics Workbench ID: 149465
• ChEMBL ID: CHEMBL44426
• Mol file: 198480-55-6.mol

Synonyms:2-(4-hydroxyphenyl)-3-methyl-1-(4-(2-piperidin-1-yl-ethoxy)-benzyl)-1H-indol-5-ol;2-(4-hydroxyphenyl)-3-methyl-1-(4-(2-piperidin-1-yl-ethoxy)-benzyl)-1H-indol-5-ol hydrochloride;ERA-923;ERA923

Chemical Property of Pipendoxifene

Chemical Property:

• Vapor Pressure: 1.93E-19mmHg at 25°C
• Refractive Index: 1.628
• Boiling Point: 685.8°Cat760mmHg
• PKA: 10.12±0.15(Predicted)
• Flash Point: 368.6°C
• PSA: 57.86000
• Density: 1.2g/cm³
• LogP: 5.87880
• Storage Temp.: Refrigerator
• Solubility.: DMSO (Slightly), Methanol (Slightly)
• XLogP3: 5.8
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 7
• Exact Mass: 456.24129289
• Heavy Atom Count: 34
• Complexity: 611

Purity/Quality:

99% ^*data from raw suppliers

Pipendoxifene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(N(C2=C1C=C(C=C2)O)CC3=CC=C(C=C3)OCCN4CCCCC4)C5=CC=C(C=C5)O
• Recent ClinicalTrials: ERA-923 in Treating Postmenopausal Women With Metastatic Breast Cancer
• Uses: Pipendoxifene is a 2-Ph indole selective estrogen receptor modulator (SERM) that exhibits an excellent preclin. pharmacol. profile and was selected for further development as a treatment for metastatic breast cancer.

Technology Process of Pipendoxifene

There total 1 articles about Pipendoxifene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ pipendoxifene (198480-55-6)

Guidance literature:

Refernces

• 1、 -. "Methods of treating breast disorders". . . Retrieved 2008/06/13.
• 2、 -. "Methods of treating neuropeptide Y-related conditions". . . Retrieved 2008/06/13.