1-(carboxymethyl)-9-methoxy-2-methyl-3,4,5,6,7,8-hexahydro-1H-phenanth rene-2-carboxylic acid

Base Information

Chemical Name:1-(carboxymethyl)-9-methoxy-2-methyl-3,4,5,6,7,8-hexahydro-1H-phenanth rene-2-carboxylic acid
CAS No.:6636-47-1
Molecular Formula:C₁₉H₂₄O₅
Molecular Weight:332.397
Hs Code.:
Mol file:6636-47-1.mol

Synonyms:NSC 51554

Suppliers and Price of 1-(carboxymethyl)-9-methoxy-2-methyl-3,4,5,6,7,8-hexahydro-1H-phenanth rene-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 1-(carboxymethyl)-9-methoxy-2-methyl-3,4,5,6,7,8-hexahydro-1H-phenanth rene-2-carboxylic acid

Chemical Property:

Vapor Pressure:8.26E-14mmHg at 25°C
Boiling Point:569.5°C at 760 mmHg
PKA:4.46±0.40(Predicted)
Flash Point:205.5°C
PSA：83.83000
Density:1.231g/cm³
LogP:3.16940

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-(carboxymethyl)-9-methoxy-2-methyl-3,4,5,6,7,8-hexahydro-1H-phenanth rene-2-carboxylic acid

There total 5 articles about 1-(carboxymethyl)-9-methoxy-2-methyl-3,4,5,6,7,8-hexahydro-1H-phenanth rene-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (+/-)-(9-methoxy-2-methyl-2-carboxy-3.4.5.6.7.8-hexahydro-2H-phenanthrylidene-(1seqtrans))-acetic acid

: 6636-47-1
(2-carboxy-9-methoxy-2-methyl-1,2,3,4,5,6,7,8-octahydro-[1]phenanthryl)-acetic acid

Guidance literature:: Multi-step reaction with 4 steps

2: aq. NaOH solution; potassium permanganate

3: zinc; benzene; diethyl ether

4: thionyl chloride; pyridine; benzene / Erwaermen einer Loesung des Reaktionsprodukts in Benzol mit methanol. Kalilauge und Behandeln einer wss. Loesung der erhaltenen Kalium-Salze mit Natrium-Amalgam

With pyridine; sodium hydroxide; potassium permanganate; thionyl chloride; diethyl ether; zinc; benzene;
DOI:10.1021/ja01255a018

Reference yield:

: (+/-)-(9-methoxy-2-methyl-2-methoxycarbonyl-3.4.5.6.7.8-hexahydro-2H-phenanthrylidene-(1seqtrans))-acetic acid methyl ester

: 6636-47-1
(2-carboxy-9-methoxy-2-methyl-1,2,3,4,5,6,7,8-octahydro-[1]phenanthryl)-acetic acid

Guidance literature:: Multi-step reaction with 3 steps

1: aq. NaOH solution; potassium permanganate

2: zinc; benzene; diethyl ether

3: thionyl chloride; pyridine; benzene / Erwaermen einer Loesung des Reaktionsprodukts in Benzol mit methanol. Kalilauge und Behandeln einer wss. Loesung der erhaltenen Kalium-Salze mit Natrium-Amalgam

With pyridine; sodium hydroxide; potassium permanganate; thionyl chloride; diethyl ether; zinc; benzene;
DOI:10.1021/ja01255a018

Reference yield:

: 860552-53-0
9-methoxy-2-methyl-1-oxo-1,2,3,4,5,6,7,8-octahydro-phenanthrene-2-carboxylic acid methyl ester

: 6636-47-1
(2-carboxy-9-methoxy-2-methyl-1,2,3,4,5,6,7,8-octahydro-[1]phenanthryl)-acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: zinc; benzene; diethyl ether

2: thionyl chloride; pyridine; benzene / Erwaermen einer Loesung des Reaktionsprodukts in Benzol mit methanol. Kalilauge und Behandeln einer wss. Loesung der erhaltenen Kalium-Salze mit Natrium-Amalgam

With pyridine; thionyl chloride; diethyl ether; zinc; benzene;
DOI:10.1021/ja01255a018