Formamide, N-[2-methyl-1-(phenylthio)propyl]-

Base Information

• Chemical Name: Formamide, N-[2-methyl-1-(phenylthio)propyl]-
• CAS No.: 109053-99-8
• Molecular Formula: C11H15NOS
• Molecular Weight: 209.312
• DSSTox Substance ID: DTXSID60404222
• Mol file: 109053-99-8.mol

Synonyms:109053-99-8;Formamide, N-[2-methyl-1-(phenylthio)propyl]-;DTXSID60404222

Chemical Property of Formamide, N-[2-methyl-1-(phenylthio)propyl]-

Chemical Property:

• XLogP3: 3.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 209.08743528
• Heavy Atom Count: 14
• Complexity: 167

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)C(NC=O)SC1=CC=CC=C1

Technology Process of Formamide, N-[2-methyl-1-(phenylthio)propyl]-

There total 4 articles about Formamide, N-[2-methyl-1-(phenylthio)propyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

thiophenol (108-98-5) + N,N-Bis<2-methyl-1-(trimethylsiloxy)propyl>formamide → N-<2-Methyl-1-(phenylsulfanyl)propyl>formamide (109053-99-8)

Guidance literature:

With trimethylsilyl trifluoromethanesulfonate; In tetrachloromethane; for 1h; Ambient temperature;

DOI:10.1039/P19960000907

Reference yield: 74.0%

1-<1-(formylamino)-2-methylpropyl>benzotriazole (130291-04-2) + thiophenol (108-98-5) → N-<2-Methyl-1-(phenylsulfanyl)propyl>formamide (109053-99-8)

Guidance literature:

With ethanol; sodium; for 96h; Ambient temperature;

DOI:10.1055/s-1993-25788

Reference yield: 68.0%

thiophenol (108-98-5) + N-(2-Methyl-1-trimethylsilanyloxy-propyl)-formamide (109053-90-9) → N-<2-Methyl-1-(phenylsulfanyl)propyl>formamide (109053-99-8)

Guidance literature:

With trimethylsilyl trifluoromethanesulfonate; In tetrachloromethane; for 0.166667h; Ambient temperature;

DOI:10.1039/p19960000895

upstream raw materials:

1-<1-(formylamino)-2-methylpropyl>benzotriazole

thiophenol

N-(2-Methyl-1-trimethylsilanyloxy-propyl)-formamide