6H-Purin-6-one, 1,9-dihydro-9-[[1-(hydroxyMethyl)-2-(triphenylMethoxy)ethoxy]Methyl]-2-[(triphenylMethyl)aMino]-

Base Information

Chemical Name:6H-Purin-6-one, 1,9-dihydro-9-[[1-(hydroxyMethyl)-2-(triphenylMethoxy)ethoxy]Methyl]-2-[(triphenylMethyl)aMino]-
CAS No.:109082-85-1
Molecular Formula:C47H41N5O4
Molecular Weight:739.874
Hs Code.:
Mol file:109082-85-1.mol

Synonyms:.N-trityl-2-(2-amino-1,6-dihydro-6-oxopuryn-9-yl)methoxy-3-trityloxy-propan-1-ol;N-trityl-2-(2-Amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-3-trityloxy-propan-1-ol;

Suppliers and Price of 6H-Purin-6-one, 1,9-dihydro-9-[[1-(hydroxyMethyl)-2-(triphenylMethoxy)ethoxy]Methyl]-2-[(triphenylMethyl)aMino]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
N,O-Ditrityl Ganciclovir
25mg
$ 460.00

TRC
N,O-DitritylGanciclovir
250mg
$ 495.00

Medical Isotopes, Inc.
N,O-DitritylGanciclovir
1 g
$ 2350.00

Medical Isotopes, Inc.
N,O-DitritylGanciclovir
250 mg
$ 950.00

Total 1 raw suppliers

Chemical Property of 6H-Purin-6-one, 1,9-dihydro-9-[[1-(hydroxyMethyl)-2-(triphenylMethoxy)ethoxy]Methyl]-2-[(triphenylMethyl)aMino]-

Chemical Property:

PKA:9.27±0.20(Predicted)
PSA：114.29000
Density:1.21±0.1 g/cm3(Predicted)
LogP:7.94030
Solubility.:Chloroform, Ethyl Acetate, Methanol

Purity/Quality:

98% ^*data from raw suppliers

N,O-Ditrityl Ganciclovir ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses N,O-Ditrityl Ganciclovir is an Impurity of Ganciclovir (G235000), a sugar modified acyclic analogue of guanosine (G837900).

Technology Process of 6H-Purin-6-one, 1,9-dihydro-9-[[1-(hydroxyMethyl)-2-(triphenylMethoxy)ethoxy]Methyl]-2-[(triphenylMethyl)aMino]-

There total 1 articles about 6H-Purin-6-one, 1,9-dihydro-9-[[1-(hydroxyMethyl)-2-(triphenylMethoxy)ethoxy]Methyl]-2-[(triphenylMethyl)aMino]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

: 82410-32-0
ganciclovir

: 76-83-5
trityl chloride

: 109082-85-1
N²-trityl-9-<(3-hydroxy-2-propoxy-1-trityloxy)methyl>guanine

Guidance literature:: With dmap; triethylamine; In N,N-dimethyl-formamide; at 50 ℃; for 9.41667h;
DOI:10.3998/ark.5550190.0012.215

Reference yield: 74.0%

: 40224-47-3
azidovaline

: 109082-85-1
N²-trityl-9-<(3-hydroxy-2-propoxy-1-trityloxy)methyl>guanine

: 1219792-43-4
N-trytil-2-(2-amino-1,6-dihydro-6-oxopurin-9-yl)methoxy-3-trityloxy-1'-propanyl-2'-(S)-azido-3'-methylbutanoate

Guidance literature:: azidovaline; With dicyclohexyl-carbodiimide; In dichloromethane; at 0 ℃; for 0.5h;

N²-trityl-9-<(3-hydroxy-2-propoxy-1-trityloxy)methyl>guanine; With dmap; triethylamine; In dichloromethane; N,N-dimethyl-formamide; at 25 ℃; for 17h;
DOI:10.3998/ark.5550190.0012.215

Reference yield:

: 109082-85-1
N²-trityl-9-<(3-hydroxy-2-propoxy-1-trityloxy)methyl>guanine

: 88110-89-8
9-<(1-acetoxy-2-hydroxymethyl)ethoxymethyl>guanine

Guidance literature:: Multi-step reaction with 2 steps

1: dicyclohexyl-carbodiimide; triethylamine

2: trifluoroacetic acid / dichloromethane / 3.17 h / 15 °C

With triethylamine; dicyclohexyl-carbodiimide; trifluoroacetic acid; In dichloromethane;
DOI:10.1080/00397911.2011.651249