Pyrrolidine, 3,4-diphenyl-, (3R,4R)-

Base Information

• Chemical Name: Pyrrolidine, 3,4-diphenyl-, (3R,4R)-
• CAS No.: 109428-67-3
• Molecular Formula: C16H17N
• Molecular Weight: 223.31300
• Mol file: 109428-67-3.mol

Synonyms:(S,S)-3,4-diphenylpyrrolidine;(3R,4R)-diphenylpyrrolidine;(3R,4R)-3,4-diphenylpyrrolidine;(3R,4R)-3,4-Diphenyl-pyrrolidine;

Chemical Property of Pyrrolidine, 3,4-diphenyl-, (3R,4R)-

Chemical Property:

• PSA: 12.03000
• LogP: 3.48600

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Pyrrolidine, 3,4-diphenyl-, (3R,4R)-

There total 17 articles about Pyrrolidine, 3,4-diphenyl-, (3R,4R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

N-Benzyl-3,4-diphenylpyrrolidine (4209-77-2,118989-09-6) → 3,4-diphenyl-trans-pyrrolidine (73082-07-2,73556-67-9,109428-67-3,119067-17-3,144901-29-1,148616-43-7)

Guidance literature:

With ammonium formate; palladium on activated charcoal; In methanol;

DOI:10.1016/S0040-4020(01)87128-3

Reference yield: 94.0%

(3R,4R)-1-phenylmethyl-3,4-diphenylpyrrolidine → trans-(3R,4R)-diphenylpyrrolidine (109428-67-3)

Guidance literature:

With formic acid; palladium on activated charcoal; In methanol; for 48h;

DOI:10.1016/S0040-4020(01)80176-9

Reference yield: 30.0%

3,4-Diphenylpyrrolidine N-ethylcarbamate → 3,4-diphenyl-trans-pyrrolidine (73082-07-2,73556-67-9,109428-67-3,119067-17-3,144901-29-1,148616-43-7)

Guidance literature:

With potassium hydroxide; In methanol; for 72h; Heating;

DOI:10.1016/S0040-4020(01)81877-9

upstream raw materials:

N-Benzyl-3,4-diphenylpyrrolidine

3,4-diphenyl-trans-N-(1'-hydroxy-2'-butyl)-pyrrolidine

(-)-(2R,3R)-2,3-diphenyl-1,4-butanediol

(3R,4R)-3,4-Diphenyl-pyrrolidine-1-carbaldehyde

Downstream raw materials:

(3R,3'R,4R,4'R)-3,3',4,4'-tetraphenyl-1,1'-ethylenedipyrrolidine

(3R,3'R,4R,4'R)-3,3',4,4'-tetraphenyl-1,1'-oxalyldipyrrolidine

2-methyl-3,4-diphenyl-pyrrolidine-1-carboxylic acid tert-butyl ester