p-Hydroxyfelbamate

Base Information

Chemical Name:p-Hydroxyfelbamate
CAS No.:109482-28-2
Molecular Formula:C₁₁H₁₄N₂O₅
Molecular Weight:254.243
Hs Code.:
DSSTox Substance ID:DTXSID201344225
Nikkaji Number:J440.348G
Wikidata:Q27149625
Metabolomics Workbench ID:71690

Synonyms:p-Hydroxyfelbamate;para-Hydroxy Felbamate;109482-28-2;2-(4-hydroxyphenyl)-1,3-propanediol dicarbamate;[3-carbamoyloxy-2-(4-hydroxyphenyl)propyl] Carbamate;CHEBI:80584;DTXSID201344225;Q27149625;carbamic acid [3-carbamoyloxy-2-(4-hydroxyphenyl)propyl] ester

Suppliers and Price of p-Hydroxyfelbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of p-Hydroxyfelbamate

Chemical Property:

XLogP3:0.3
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:254.09027155
Heavy Atom Count:18
Complexity:271

Purity/Quality:: > 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C(COC(=O)N)COC(=O)N)O

Technology Process of p-Hydroxyfelbamate

There total 5 articles about p-Hydroxyfelbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2-(4-hydroxyphenyl)-1,3-propanediol bischloroformate

: 109482-28-2
2-(4-hydroxyphenyl)-1,3-propanediol dicarbamate

Guidance literature:: With ammonia; at 0 ℃; for 0.5h; Yield given;
DOI:10.1016/S0040-4020(01)88100-X

Reference yield:

: 104-01-8
4-Methoxyphenylacetic acid

: 109482-28-2
2-(4-hydroxyphenyl)-1,3-propanediol dicarbamate

Guidance literature:: Multi-step reaction with 5 steps

1: 58 percent / n-butyllithium / tetrahydrofuran; hexane / at dry ice temp., 2 h and RT, 30 min

2: 51 percent / borane*THF / methanol / 6 h / 0 °C

3: tetrahydrofuran / 2.5 h / Ambient temperature

4: boron tribromide / CH₂Cl₂ / 2 h / 25 °C

5: ammonia / 0.5 h / 0 °C

With n-butyllithium; borane-THF; ammonia; boron tribromide; In tetrahydrofuran; methanol; hexane; dichloromethane;
DOI:10.1016/S0040-4020(01)88100-X

Reference yield:

: 53181-45-6
2-(4-methoxyphenyl)propanedioic acid

: 109482-28-2
2-(4-hydroxyphenyl)-1,3-propanediol dicarbamate

Guidance literature:: Multi-step reaction with 4 steps

1: 51 percent / borane*THF / methanol / 6 h / 0 °C

2: tetrahydrofuran / 2.5 h / Ambient temperature

3: boron tribromide / CH₂Cl₂ / 2 h / 25 °C

4: ammonia / 0.5 h / 0 °C

With borane-THF; ammonia; boron tribromide; In tetrahydrofuran; methanol; dichloromethane;
DOI:10.1016/S0040-4020(01)88100-X