2-Hydroxyfelbamate

Base Information

Chemical Name:2-Hydroxyfelbamate
CAS No.:109482-32-8
Molecular Formula:C₁₁H₁₄N₂O₅
Molecular Weight:254.243
Hs Code.:
UNII:735K2T4YFB
DSSTox Substance ID:DTXSID60439317
Nikkaji Number:J440.349E
Wikidata:Q27149624
Metabolomics Workbench ID:71697
Mol file:109482-32-8.mol

Synonyms:2-Hydroxyfelbamate;109482-32-8;2-Hydroxy Felbamate;(3-carbamoyloxy-2-hydroxy-2-phenylpropyl) carbamate;Dicarbamic acid 2-(2-hydroxyphenyl)trimethylene ester;2-hydroxy-2-phenyl-1,3-propanediol dicarbamate;735K2T4YFB;CHEBI:80583;DTXSID60439317;FT-0669636;1,2,3-Propanetriol, 2-phenyl-, 1,3-dicarbamate;2-Hydroxy-2-phenyl-1,3-propanediol 1,3-dicarbamate;Q27149624;(3-Aminocarbonyloxy-2-oxidanyl-2-phenyl-propyl) carbamate;carbamic acid (3-carbamoyloxy-2-hydroxy-2-phenyl-propyl) ester

Suppliers and Price of 2-Hydroxyfelbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
2-Hydroxy felbamate
1mg
$ 460.00

TRC
2-HydroxyFelbamate
2.5mg
$ 185.00

American Custom Chemicals Corporation
2-HYDROXY FELBAMATE 95.00%
25MG
$ 1963.50

American Custom Chemicals Corporation
2-HYDROXY FELBAMATE 95.00%
2.5MG
$ 715.00

American Custom Chemicals Corporation
2-HYDROXY FELBAMATE 95.00%
1MG
$ 367.50

Total 7 raw suppliers

Chemical Property of 2-Hydroxyfelbamate

Chemical Property:

PSA：126.85000
LogP:1.09240
Storage Temp.:Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility.:DMSO (Slightly), Methanol (Slightly)
XLogP3:-0.5
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:254.09027155
Heavy Atom Count:18
Complexity:284

Purity/Quality:

97% ^*data from raw suppliers

2-Hydroxy felbamate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(COC(=O)N)(COC(=O)N)O
Uses A metabolite of the antiepileptic drug Felbamate (F231000).

Technology Process of 2-Hydroxyfelbamate

There total 5 articles about 2-Hydroxyfelbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 109482-31-7
4-phenyl-1,3-dioxolan-2-one-4-yl-methanol carbamate

: 109482-32-8
2-hydroxy-2-phenyl-1,3-propanediol dicarbamate

Guidance literature:: With ammonia; for 24h; Ambient temperature;
DOI:10.1016/S0040-4020(01)88100-X

Reference yield:

: 1570-95-2
2-phenylpropane-1, 3-diol

: 109482-32-8
2-hydroxy-2-phenyl-1,3-propanediol dicarbamate

Guidance literature:: Multi-step reaction with 5 steps

1: antipyrine / tetrahydrofuran; toluene; CHCl₃ / Ambient temperature

2: dibenzoyl peroxide, NBS / CCl₄ / 96 h / Heating; Irradiation

3: NH₃ / 0.5 h / 0 °C

4: 56 percent / silver acetate / acetic acid; H₂O / 22 h / Ambient temperature

5: 94 percent / ammonia / 24 h / Ambient temperature

With N-Bromosuccinimide; antipyrine; ammonia; silver(I) acetate; dibenzoyl peroxide; In tetrahydrofuran; tetrachloromethane; chloroform; water; acetic acid; toluene;
DOI:10.1016/S0040-4020(01)88100-X

Reference yield:

: 109482-29-3
C₁₁H₁₀Cl₂O₄

: 109482-32-8
2-hydroxy-2-phenyl-1,3-propanediol dicarbamate

Guidance literature:: Multi-step reaction with 4 steps

1: dibenzoyl peroxide, NBS / CCl₄ / 96 h / Heating; Irradiation

2: NH₃ / 0.5 h / 0 °C

3: 56 percent / silver acetate / acetic acid; H₂O / 22 h / Ambient temperature

4: 94 percent / ammonia / 24 h / Ambient temperature

With N-Bromosuccinimide; ammonia; silver(I) acetate; dibenzoyl peroxide; In tetrachloromethane; water; acetic acid;
DOI:10.1016/S0040-4020(01)88100-X