Benzyl(ethenyl)oxo(phenyl)-lambda~5~-phosphane

Base Information

• Chemical Name: Benzyl(ethenyl)oxo(phenyl)-lambda~5~-phosphane
• CAS No.: 109632-24-8
• Molecular Formula: C15H15OP
• Molecular Weight: 242.257
• DSSTox Substance ID: DTXSID30545717
• Nikkaji Number: J408.222B
• Mol file: 109632-24-8.mol

Synonyms:109632-24-8;DTXSID30545717;Benzyl(ethenyl)oxo(phenyl)-lambda~5~-phosphane

Chemical Property of Benzyl(ethenyl)oxo(phenyl)-lambda~5~-phosphane

Chemical Property:

• XLogP3: 2.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 242.086052095
• Heavy Atom Count: 17
• Complexity: 285

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C=CP(=O)(CC1=CC=CC=C1)C2=CC=CC=C2

Technology Process of Benzyl(ethenyl)oxo(phenyl)-lambda~5~-phosphane

There total 1 articles about Benzyl(ethenyl)oxo(phenyl)-lambda~5~-phosphane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

Vinyl bromide (593-60-2,25951-54-6) + benzyl (phenyl)phosphine oxide (20335-99-3,20428-90-4,177334-60-0) → benzylphenylvinylphosphine oxide (109632-24-8)

Guidance literature:

With triethylamine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In toluene; at 80 ℃; for 8h;

DOI:10.1055/s-1986-31753

Reference yield: 44.0%

benzylphenylvinylphosphine oxide (109632-24-8) + 1-Bromo-3-[(E)-2-((S)-methyl-phenyl-phosphinoyl)-vinyl]-benzene (153279-10-8) → 1-[(E)-2-(Benzyl-phenyl-phosphinoyl)-vinyl]-3-[(E)-2-((S)-methyl-phenyl-phosphinoyl)-vinyl]-benzene

Guidance literature:

With triethylamine; triphenylphosphine; palladium diacetate; In N,N-dimethyl-formamide; at 135 ℃; for 36h;

DOI:10.1016/S0957-4166(00)80060-9

Reference yield: 34.0%

benzylphenylvinylphosphine oxide (109632-24-8) + acrylic acid methyl ester (292638-85-8,9003-21-8,96-33-3) → (+/-)-(E)-(2-methoxycarbonylvinyl)(benzyl)phenylphosphane oxide + dimethylfumarate (624-49-7)

Guidance literature:

With 1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene; [2-isopropoxy-5-nitro-benzylidene][RuCl₂]; In dichloromethane; at 45 ℃; for 24h;

DOI:10.1002/adsc.200505463

upstream raw materials:

Vinyl bromide

benzyl (phenyl)phosphine oxide

Downstream raw materials:

(2R,3aR)-2-(Benzyl-phenyl-phosphinoyl)-6,6-dimethyl-hexahydro-pyrrolo[1,2-b]isoxazole

(2S,3aS)-2-(Benzyl-phenyl-phosphinoyl)-6,6-dimethyl-hexahydro-pyrrolo[1,2-b]isoxazole

dimethylfumarate