(3-Iodobenzyl)trozamicol

Base Information

Chemical Name:(3-Iodobenzyl)trozamicol
CAS No.:148519-95-3
Molecular Formula:C₂₃H₂₉IN₂O
Molecular Weight:476.401
Hs Code.:
DSSTox Substance ID:DTXSID30164003
Wikidata:Q83033028
Mol file:148519-95-3.mol

Synonyms:(3-iodobenzyl)trozamicol;(m-iodobenzyl)trozamicol;3-iodobenzyl-4-azavesamicol;4-hydroxy-1-(3-iodobenzyl)-3-(4-phenylpiperidinyl)piperidine;meta-iodobenzyltrozamicol;MIBT-3;trans(+-)-isomer of (3-iodobenzyl)trozamicol;trans-(+)-isomer of (3-iodobenzyl)trozamicol

Suppliers and Price of (3-Iodobenzyl)trozamicol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of (3-Iodobenzyl)trozamicol

Chemical Property:

Vapor Pressure:1.11E-13mmHg at 25°C
Boiling Point:566.7°Cat760mmHg
Flash Point:296.5°C
PSA：26.71000
Density:1.442g/cm³
LogP:3.98180
XLogP3:4.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:476.13246
Heavy Atom Count:27
Complexity:448

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCC1C2=CC=CC=C2)C3CN(CCC3O)CC4=CC(=CC=C4)I
Isomeric SMILES:C1CN(C[C@@H]([C@H]1O)N2CCC(CC2)C3=CC=CC=C3)CC4=CC(=CC=C4)I

Technology Process of (3-Iodobenzyl)trozamicol

There total 2 articles about (3-Iodobenzyl)trozamicol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (+)-1-benzoyl-4-hydroxy-3-(4-phenylpiperidinyl)piperidine hydrochloride

: 148519-95-3
(+/-)-4-hydroxy-1-(3-iodobenzyl)-3-(4-phenylpiperidinyl)piperidine

Guidance literature:: Multi-step reaction with 2 steps

1: 75 percent / 6N aq. HCl / 24 h / Heating

2: NaHCO₃ / ethanol; H₂O / 24 h / Heating

With hydrogenchloride; sodium hydrogencarbonate; In ethanol; water;
DOI:10.1021/jm00060a005