8,9-dihydro-8-(1-hydroxy-1-methylethyl)-2H-furo[2,3-h]1-benzopyran-2-one

Base Information

Chemical Name:8,9-dihydro-8-(1-hydroxy-1-methylethyl)-2H-furo[2,3-h]1-benzopyran-2-one
CAS No.:1147-29-1
Molecular Formula:C₁₄H₁₄O₄
Molecular Weight:246.263
Hs Code.:
European Community (EC) Number:683-146-3
DSSTox Substance ID:DTXSID60921469
Nikkaji Number:J80.201H
Wikidata:Q27126979
ChEMBL ID:CHEMBL155115
Mol file:1147-29-1.mol

Synonyms:columbianetin;columbianetin, (+-)-isomer;columbianetin, (S)-isomer

Suppliers and Price of 8,9-dihydro-8-(1-hydroxy-1-methylethyl)-2H-furo[2,3-h]1-benzopyran-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 15 raw suppliers

Chemical Property of 8,9-dihydro-8-(1-hydroxy-1-methylethyl)-2H-furo[2,3-h]1-benzopyran-2-one

Chemical Property:

Vapor Pressure:1.25E-08mmHg at 25°C
Boiling Point:443oC at 760 mmHg
Flash Point:171.9oC
PSA：59.67000
Density:1.334g/cm3
LogP:1.86740
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:246.08920892
Heavy Atom Count:18
Complexity:387

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C1CC2=C(O1)C=CC3=C2OC(=O)C=C3)O

Technology Process of 8,9-dihydro-8-(1-hydroxy-1-methylethyl)-2H-furo[2,3-h]1-benzopyran-2-one

There total 9 articles about 8,9-dihydro-8-(1-hydroxy-1-methylethyl)-2H-furo[2,3-h]1-benzopyran-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 484-14-0
osthenol

: 1147-29-1,3804-70-4,26079-34-5,52842-47-4
columbianetin

Guidance literature:: With potassium carbonate; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 20 ℃; for 8h; Inert atmosphere;
DOI:10.1016/j.bmcl.2020.127633

Reference yield: 75.0%

: 1351118-96-1
C₁₄H₁₄O₄

: 1147-29-1,3804-70-4,26079-34-5,52842-47-4
columbianetin

Guidance literature:: With Echavarren's catalyst; In dichloromethane; for 16h; Inert atmosphere; Reflux;
DOI:10.1016/j.tetlet.2011.10.036

Reference yield: 71.0%

: 27421-19-8
7-(2-methylbut-3-en-2-yloxy)-2H-chromen-2-one

: 1147-29-1,3804-70-4,26079-34-5,52842-47-4
columbianetin

Guidance literature:: 7-(2-methylbut-3-en-2-yloxy)-2H-chromen-2-one; With sodium hydrogencarbonate; In water; at 75 ℃; for 2h;

With 3-chloro-benzenecarboperoxoic acid; In water; at 50 ℃; for 20h;
DOI:10.1016/j.tetlet.2012.11.150