1,5(2H)-Pyrimidinedicarboxylic acid, 3,6-dihydro-4-methyl-6-(2-nitrophenyl)-2-oxo-, 5-(cyclopropylmethyl) 1-heptyl ester

Base Information

Chemical Name:1,5(2H)-Pyrimidinedicarboxylic acid, 3,6-dihydro-4-methyl-6-(2-nitrophenyl)-2-oxo-, 5-(cyclopropylmethyl) 1-heptyl ester
CAS No.:110448-23-2
Molecular Formula:C24H31N3O7
Molecular Weight:473.526
Hs Code.:
Mol file:110448-23-2.mol

Synonyms:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1,5(2H)-Pyrimidinedicarboxylic acid, 3,6-dihydro-4-methyl-6-(2-nitrophenyl)-2-oxo-, 5-(cyclopropylmethyl) 1-heptyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1,5(2H)-Pyrimidinedicarboxylic acid, 3,6-dihydro-4-methyl-6-(2-nitrophenyl)-2-oxo-, 5-(cyclopropylmethyl) 1-heptyl ester

There total 5 articles about 1,5(2H)-Pyrimidinedicarboxylic acid, 3,6-dihydro-4-methyl-6-(2-nitrophenyl)-2-oxo-, 5-(cyclopropylmethyl) 1-heptyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 121484-75-1
5-<(cyclopropylmethoxy)carbonyl>-3-<(heptyloxy)carbonyl>-1-N-(methoxymethyl)-6-methyl-4-(2-nitrophenyl)dihydropyrimidin-2-one

: 110448-23-2
5-[(cyclopropylmethoxy)carbonyl]-3-[(heptyloxy)carbonyl]-6-methyl-4-(2-nitrophenyl)-3,4-dihydropyrimidin-2(1H)-one

Guidance literature:: With hydrogenchloride; In chloroform; for 2h; Heating;
DOI:10.1021/jm00130a029

Reference yield: 6.0%

: 33758-34-8
n-heptyl chloroformate

: 110448-30-1
5-<(cyclopropylmethoxy)carbonyl>-6-methyl-4-(2-nitrophenyl)-3,4-dihydropyrimidin-2(1H)-one

: 110448-23-2
5-[(cyclopropylmethoxy)carbonyl]-3-[(heptyloxy)carbonyl]-6-methyl-4-(2-nitrophenyl)-3,4-dihydropyrimidin-2(1H)-one

Guidance literature:: With sodium hydride; In tetrahydrofuran;
DOI:10.1016/S0040-4039(00)82880-4

Reference yield:

: 33758-34-8
n-heptyl chloroformate

: 110448-23-2
5-[(cyclopropylmethoxy)carbonyl]-3-[(heptyloxy)carbonyl]-6-methyl-4-(2-nitrophenyl)-3,4-dihydropyrimidin-2(1H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) NaH / 1.) THF, room temperature, 20 min, 2.) room temperature, 20 min

2: 100 percent / conc. HCl / CHCl₃ / 2 h / Heating

With hydrogenchloride; sodium hydride; In chloroform;
DOI:10.1021/jm00130a029