2,4,5,6-Tetrafluorobenzene-1,3-dicarbonyl dichloride

Base Information

• Chemical Name: 2,4,5,6-Tetrafluorobenzene-1,3-dicarbonyl dichloride
• CAS No.: 110649-97-3
• Molecular Formula: C₈Cl₂F₄O₂
• Molecular Weight: 274.986
• DSSTox Substance ID: DTXSID20596091
• Nikkaji Number: J1.179.284G
• Wikidata: Q82491229
• Mol file: 110649-97-3.mol

Synonyms:110649-97-3;tetrafluoroisophthaloylchloride;2,4,5,6-Tetrafluorobenzene-1,3-dicarbonyl dichloride;SCHEMBL6538271;DTXSID20596091

Chemical Property of 2,4,5,6-Tetrafluorobenzene-1,3-dicarbonyl dichloride

Chemical Property:

• PSA: 34.14000
• LogP: 3.00100
• XLogP3: 3.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 2
• Exact Mass: 273.9211473
• Heavy Atom Count: 16
• Complexity: 286

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1(=C(C(=C(C(=C1F)F)F)C(=O)Cl)F)C(=O)Cl

Technology Process of 2,4,5,6-Tetrafluorobenzene-1,3-dicarbonyl dichloride

There total 1 articles about 2,4,5,6-Tetrafluorobenzene-1,3-dicarbonyl dichloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,4,5,6-tetrafluoroisophthalic acid (1551-39-9) → 2,4,5,6-tetrafluorobenzene-1,3-dicarboxylic acid chloride (110649-97-3)

Guidance literature:

With thionyl chloride; for 48h; Schlenk technique; Reflux;

DOI:10.1021/jacs.9b11290

upstream raw materials:

2,4,5,6-tetrafluoroisophthalic acid