1-[(4-Fluorophenyl)methyl]azetidin-3-ol

Base Information

Chemical Name:1-[(4-Fluorophenyl)methyl]azetidin-3-ol
CAS No.:111043-49-3
Molecular Formula:C10H12FNO
Molecular Weight:181.21
Hs Code.:
European Community (EC) Number:891-951-8
DSSTox Substance ID:DTXSID501280210
Nikkaji Number:J583.090G
Mol file:111043-49-3.mol

Synonyms:1-[(4-fluorophenyl)methyl]azetidin-3-ol;111043-49-3;1-[(4-Fluorophenyl)methyl]-3-azetidinol;1-(4-fluorobenzyl)azetidin-3-ol;SCHEMBL2922811;JKNYOFXNAYHDJV-UHFFFAOYSA-N;DTXSID501280210;AKOS012391714;AB91990;CS-0238467;EN300-196041;F8887-7451

Suppliers and Price of 1-[(4-Fluorophenyl)methyl]azetidin-3-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-[(4-Fluorophenyl)methyl]-3-azetidinol
50mg
$ 175.00

AK Scientific
1-[(4-Fluorophenyl)methyl]azetidin-3-ol
100mg
$ 310.00

AK Scientific
1-[(4-Fluorophenyl)methyl]azetidin-3-ol
5g
$ 2222.00

Acrotein
1-[(4-Fluorophenyl)methyl]-3-azetidinol 97%
1g
$ 412.50

ACHEMBLOCK
1-[(4-Fluorophenyl)methyl]-3-azetidinol 95%
250MG
$ 220.00

Total 6 raw suppliers

Chemical Property of 1-[(4-Fluorophenyl)methyl]azetidin-3-ol

Chemical Property:

PSA：23.47000
LogP:0.94010
XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:181.090292168
Heavy Atom Count:13
Complexity:162

Purity/Quality:

97% ^*data from raw suppliers

1-[(4-Fluorophenyl)methyl]-3-azetidinol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(CN1CC2=CC=C(C=C2)F)O

Technology Process of 1-[(4-Fluorophenyl)methyl]azetidin-3-ol

There total 4 articles about 1-[(4-Fluorophenyl)methyl]azetidin-3-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 111043-43-7
1-(4-fluorobenzyl)-3-trimethylsilyloxy-azetidine

: 111043-49-3
1-(p-fluorobenzyl)-3-hydroxyazetidine

Guidance literature:: With sodium methylate; In methanol; for 2h; Ambient temperature;

Reference yield: 61.0%

: 111043-49-3
1-(p-fluorobenzyl)-3-hydroxyazetidine

Guidance literature:

Reference yield:

: 140-75-0
para-fluorobenzylamine

: 111043-49-3
1-(p-fluorobenzyl)-3-hydroxyazetidine

Guidance literature:: Multi-step reaction with 2 steps

1: 26 percent / triethylamine / acetonitrile / 72 h / Heating

2: 75 percent / sodium methoxide; / methanol / 2 h / Ambient temperature

With sodium methylate; triethylamine; In methanol; acetonitrile;