1H-Indole-3-methanol, 5-methoxy-2-methyl-1-(phenylmethyl)-

Base Information

Chemical Name:1H-Indole-3-methanol, 5-methoxy-2-methyl-1-(phenylmethyl)-
CAS No.:111055-30-2
Molecular Formula:C18H19NO2
Molecular Weight:281.354
Hs Code.:
DSSTox Substance ID:DTXSID10431104
Mol file:111055-30-2.mol

Synonyms:111055-30-2;1H-Indole-3-methanol, 5-methoxy-2-methyl-1-(phenylmethyl)-;DTXSID10431104

Suppliers and Price of 1H-Indole-3-methanol, 5-methoxy-2-methyl-1-(phenylmethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1H-Indole-3-methanol, 5-methoxy-2-methyl-1-(phenylmethyl)-

Chemical Property:

XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:281.141578849
Heavy Atom Count:21
Complexity:329

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C2=C(N1CC3=CC=CC=C3)C=CC(=C2)OC)CO

Technology Process of 1H-Indole-3-methanol, 5-methoxy-2-methyl-1-(phenylmethyl)-

There total 9 articles about 1H-Indole-3-methanol, 5-methoxy-2-methyl-1-(phenylmethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 95275-80-2
1-Benzyl-2-methyl-5-methoxy-1H-indole-3-carboxaldehyde

: 111055-30-2
3-(hydroxymethyl)-2-methyl-1-(phenylmethyl)-5-methoxyindole

Guidance literature:: With sodium tetrahydroborate; In ethanol; for 20h; Ambient temperature;

Reference yield: 63.0%

: 345960-81-8
3-(carbomethoxy)-2-methyl-1-(phenylmethyl)-5-methoxyindole

: 111055-30-2
3-(hydroxymethyl)-2-methyl-1-(phenylmethyl)-5-methoxyindole

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; at 20 ℃; for 17h;
DOI:10.1016/S0968-0896(00)00292-3

Reference yield:

: 73967-75-6
3-(carbomethoxy)-2-methyl-1-(phenylmethyl)-5-hydroxyindole

: 111055-30-2
3-(hydroxymethyl)-2-methyl-1-(phenylmethyl)-5-methoxyindole

Guidance literature:: Multi-step reaction with 2 steps

1: 57.2 percent / tetrabutylammonium bromide; aq. NaOH / 0.5 h / Heating

2: 63 percent / LiAlH₄ / tetrahydrofuran / 17 h / 20 °C

With sodium hydroxide; lithium aluminium tetrahydride; tetrabutylammomium bromide; In tetrahydrofuran;
DOI:10.1016/S0968-0896(00)00292-3