Technology Process of Butanedioic acid, (phenylmethyl)-, 4-methyl ester, (S)-
There total 3 articles about Butanedioic acid, (phenylmethyl)-, 4-methyl ester, (S)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogen; triethylamine;
Ru2Cl4((R)-(+)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl)2;
In
tetrahydrofuran; toluene;
at 35 ℃;
for 48h;
under 2206.5 Torr;
Title compound not separated from byproducts;
op = 72percent, var. cat. RuHCl*2<(+)-BINAP>;
DOI:10.1016/S0040-4039(00)96006-4
- Guidance literature:
-
With
hydrogen; triethylamine;
<((R)-(1,1'-binaphthyl-2,2'-diyl)bis(diphenylphosphine))RuCl2>2NEt3;
In
tetrahydrofuran; ethanol;
at 35 ℃;
for 48h;
under 1520 Torr;
Yield given. Yields of byproduct given. Title compound not separated from byproducts;
RuHCl-bis<(R)-(+)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl>;
- Guidance literature:
-
With
bis(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate; hydrogen; 4-isopropoxy-3,5-dioxa-4-phospha-cyclohepta[2,1-a;3,4-a']dinaphthalene;
In
dichloromethane;
at 20 ℃;
for 2h;
under 18751.9 Torr;
Reagent/catalyst;
Pressure;
Time;
Solvent;
optical yield given as %ee;
enantioselective reaction;
Reactivity;
Inert atmosphere;
DOI:10.1002/adsc.200700215
