2-(4-Methoxyphenoxy)propanoyl chloride

Base Information

Chemical Name:2-(4-Methoxyphenoxy)propanoyl chloride
CAS No.:111479-09-5
Molecular Formula:C10H11ClO3
Molecular Weight:214.64600
Hs Code.:
DSSTox Substance ID:DTXSID20540751
Mol file:111479-09-5.mol

Synonyms:2-(4-methoxyphenoxy)propanoyl chloride;111479-09-5;2-(4-Methoxy-phenoxy)-propionyl chloride;SCHEMBL10739345;DTXSID20540751;MFCD03421596;AKOS002392468;AKOS017259054;VS-04068

Suppliers and Price of 2-(4-Methoxyphenoxy)propanoyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
2-(4-Methoxyphenoxy)propanoyl chloride
500mg
$ 237.00

Total 5 raw suppliers

Chemical Property of 2-(4-Methoxyphenoxy)propanoyl chloride

Chemical Property:

PSA：35.53000
LogP:2.22790
XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:214.0396719
Heavy Atom Count:14
Complexity:188

Purity/Quality:

97% ^*data from raw suppliers

2-(4-Methoxyphenoxy)propanoyl chloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C(=O)Cl)OC1=CC=C(C=C1)OC

Technology Process of 2-(4-Methoxyphenoxy)propanoyl chloride

There total 9 articles about 2-(4-Methoxyphenoxy)propanoyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 13794-15-5,4276-73-7,4276-75-9
2-(4-methoxyphenoxy)propanoic acid

: 92818-05-8,111479-09-5
2-(4'-methoxyphenoxy)propanoic acid chloride

Guidance literature:: With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at 20 ℃; for 6h; Inert atmosphere;
DOI:10.1002/ejoc.201800656

Reference yield:

: 150-76-5
4-methoxy-phenol

: 92818-05-8,111479-09-5
2-(4'-methoxyphenoxy)propanoic acid chloride

Guidance literature:: Multi-step reaction with 3 steps

1: NaH / hexamethylphosphoric acid triamide; tetrahydrofuran / 60 °C

2: 82 percent / 85percent H₃PO₄

3: 69 percent / SOCl₂ / dimethylformamide / 1 h / Heating

With thionyl chloride; phosphoric acid; sodium hydride; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; N,N-dimethyl-formamide;
DOI:10.1021/ja00338a027

Reference yield:

: (±)-2-(p-methoxyphenoxy)propionic acid sodium salt

: 92818-05-8,111479-09-5
2-(4'-methoxyphenoxy)propanoic acid chloride

Guidance literature:: Multi-step reaction with 2 steps

1: 82 percent / 85percent H₃PO₄

2: 69 percent / SOCl₂ / dimethylformamide / 1 h / Heating

With thionyl chloride; phosphoric acid; In N,N-dimethyl-formamide;
DOI:10.1021/ja00338a027