4-Methyl-1,2,3,4-tetrahydroisoquinoline hydrochloride

Base Information

• Chemical Name: 4-Methyl-1,2,3,4-tetrahydroisoquinoline hydrochloride
• CAS No.: 111661-47-3
• Molecular Formula: C10H13N.ClH
• Molecular Weight: 183.67800
• Hs Code.: 2933499090
• DSSTox Substance ID: DTXSID70548080
• Mol file: 111661-47-3.mol

Synonyms:111661-47-3;4-Methyl-1,2,3,4-tetrahydroisoquinoline hydrochloride;4-Methyl-1,2,3,4-tetrahydroisoquinoline HCl;4-Methyl-1,2,3,4-tetrahydro-isoquinoline hydrochloride;1,2,3,4-Tetrahydro-4-methylisoquinoline Hydrochloride;4-Methyl-1,2,3,4-tetrahydroisoquinoline;hydrochloride;FEIBBSJVOAXLOY-UHFFFAOYSA-N;SCHEMBL2259898;DTXSID70548080;MFCD11501478;AKOS016842722;DS-6674;SB30691;SB47147;CS-0036832;EN300-366757;A894699;J-002615;4-Methyl-1,2,3,4-tetrahydroisoquinolinehydrochloride;4-methyl-1,2,3,4-tetrahydro-isoquinolin hydrochloride;Z1741982189;4-Methyl-1,2,3,4-tetrahydroisoquinoline--hydrogen chloride (1/1)

Chemical Property of 4-Methyl-1,2,3,4-tetrahydroisoquinoline hydrochloride

Chemical Property:

• PSA: 12.03000
• LogP: 3.02410
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 183.0814771
• Heavy Atom Count: 12
• Complexity: 133

Purity/Quality:

98%min ^*data from raw suppliers

1,2,3,4-Tetrahydro-4-methylisoquinolineHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1CNCC2=CC=CC=C12.Cl
• Uses: 1,2,3,4-Tetrahydro-4-methylisoquinoline Hydrochloride is a potent inhibitor of phenylethanolamine N-methyltransferase, an enzyme that catalyzes the formation of epinephrine.

Technology Process of 4-Methyl-1,2,3,4-tetrahydroisoquinoline hydrochloride

There total 1 articles about 4-Methyl-1,2,3,4-tetrahydroisoquinoline hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

4-methylisoquinoline (1196-39-0) → 4-methyl-1,2,3,4-tetrahydroisoquinoline hydrochloride (111661-47-3)

Guidance literature:

With hydrogenchloride; hydrogen; platinum(IV) oxide; In methanol; at 20 ℃; for 4h; under 2250.23 Torr;

upstream raw materials:

4-methylisoquinoline

Refernces