2-(3,4-Dimethoxyphenyl)sulfanylethanamine;hydrochloride

Base Information

Chemical Name:2-(3,4-Dimethoxyphenyl)sulfanylethanamine;hydrochloride
CAS No.:111708-66-8
Molecular Formula:C10H15NO2S.ClH
Molecular Weight:249.762
Hs Code.:
DSSTox Substance ID:DTXSID80548596

Synonyms:111708-66-8;SCHEMBL19462138;DTXSID80548596;2-[(3,4-Dimethoxyphenyl)sulfanyl]ethan-1-amine--hydrogen chloride (1/1)

Suppliers and Price of 2-(3,4-Dimethoxyphenyl)sulfanylethanamine;hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(3,4-Dimethoxyphenyl)sulfanylethanamine;hydrochloride

Chemical Property:

Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:249.0590276
Heavy Atom Count:15
Complexity:157

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)SCCN)OC.Cl

Technology Process of 2-(3,4-Dimethoxyphenyl)sulfanylethanamine;hydrochloride

There total 3 articles about 2-(3,4-Dimethoxyphenyl)sulfanylethanamine;hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: tert-butyl (2-((3,4-dimethoxyphenyl)thio)ethyl)carbamate

: 111708-66-8
2-((3,4-dimethoxyphenyl)thio)ethan-1-amine hydrochloride

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; water; at 0 - 20 ℃; for 3.25h;

Reference yield: 74.0%

: 107-09-5
2-bromoethylamine

: 111708-65-7
sodium 3,4-dimethoxythiophenolate

: 111708-66-8
2-((3,4-dimethoxyphenyl)thio)ethan-1-amine hydrochloride

Guidance literature:: In benzene; for 1h; Heating;
DOI:10.1139/v87-027

Reference yield:

: 700-96-9
3,4-dimethoxythiophenol

: 111708-66-8
2-((3,4-dimethoxyphenyl)thio)ethan-1-amine hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / mineral oil; tetrahydrofuran / 0.17 h / 0 - 20 °C

1.2: 16 h / 20 °C

2.1: hydrogenchloride / 1,4-dioxane; water / 3.25 h / 0 - 20 °C

With hydrogenchloride; sodium hydride; In tetrahydrofuran; 1,4-dioxane; water; mineral oil;