Propanamide, 3-[[3-(2,3-dimethylphenoxy)-2-hydroxypropyl](phenylmethyl)amino]-N-[4- (1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]-

Base Information

Chemical Name:Propanamide, 3-[[3-(2,3-dimethylphenoxy)-2-hydroxypropyl](phenylmethyl)amino]-N-[4- (1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]-
CAS No.:111794-54-8
Molecular Formula:C₃₂H₃₈N₄O₄
Molecular Weight:542.678
Hs Code.:
Mol file:111794-54-8.mol

Propanamide,
3-[[3-(2,3-dimethylphenoxy)-2-hydroxypropyl](phenylmethyl)amino]-N-[4-
(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]-

Synonyms:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Propanamide, 3-[[3-(2,3-dimethylphenoxy)-2-hydroxypropyl](phenylmethyl)amino]-N-[4- (1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]-

Chemical Property:

Purity/Quality:

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Technology Process of Propanamide, 3-[[3-(2,3-dimethylphenoxy)-2-hydroxypropyl](phenylmethyl)amino]-N-[4- (1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]-

There total 4 articles about Propanamide, 3-[[3-(2,3-dimethylphenoxy)-2-hydroxypropyl](phenylmethyl)amino]-N-[4- (1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 526-75-0
2,3-Dimethylphenol

: 111794-54-8
3-{Benzyl-[3-(2,3-dimethyl-phenoxy)-2-hydroxy-propyl]-amino}-N-[4-(4-methyl-6-oxo-1,4,5,6-tetrahydro-pyridazin-3-yl)-phenyl]-propionamide

Guidance literature:: Multi-step reaction with 2 steps

1: 83 percent / K₂CO₃ / butan-2-one / 16 h / Heating

2: propan-1-ol / Heating

With potassium carbonate; In propan-1-ol; butanone;
DOI:10.1021/jm00397a013

Reference yield:

: 111794-34-4
6-<4-(3-bromopropionamido)phenyl>-5-methyl-4,5-dihydro-3(2H)-pyridazinone

: 111794-54-8
3-{Benzyl-[3-(2,3-dimethyl-phenoxy)-2-hydroxy-propyl]-amino}-N-[4-(4-methyl-6-oxo-1,4,5,6-tetrahydro-pyridazin-3-yl)-phenyl]-propionamide

Guidance literature:: Multi-step reaction with 2 steps

1: 81 percent / propan-1-ol / 6 h / Heating

2: propan-1-ol / Heating

In propan-1-ol;
DOI:10.1021/jm00397a013

Reference yield:

: 36725-28-7
6-(4-aminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone

: 111794-54-8
3-{Benzyl-[3-(2,3-dimethyl-phenoxy)-2-hydroxy-propyl]-amino}-N-[4-(4-methyl-6-oxo-1,4,5,6-tetrahydro-pyridazin-3-yl)-phenyl]-propionamide

Guidance literature:: Multi-step reaction with 3 steps

1: 99 percent / acetonitrile / 3 h / Heating

2: 81 percent / propan-1-ol / 6 h / Heating

3: propan-1-ol / Heating

In propan-1-ol; acetonitrile;
DOI:10.1021/jm00397a013