Technology Process of Phenol, 3-[[6-(dimethylamino)-9H-purin-9-yl]methyl]-,
monohydrobromide
There total 5 articles about Phenol, 3-[[6-(dimethylamino)-9H-purin-9-yl]methyl]-,
monohydrobromide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogen bromide;
In
acetic acid;
for 0.5h;
Ambient temperature;
DOI:10.1021/jm00398a019
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 41 percent / K2CO3 / dimethylformamide / 16 h / Ambient temperature
2: 68 percent / ethanol; H2O / 15 h / Ambient temperature
3: 79 percent / conc. HBr / acetic acid / 0.5 h / Ambient temperature
With
hydrogen bromide; potassium carbonate;
In
ethanol; water; acetic acid; N,N-dimethyl-formamide;
DOI:10.1021/jm00398a019
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 85 percent / benzyltrimethylammonium hydroxide, K2CO3 / methanol; dimethylformamide / 18 h / 70 °C
2: SOCl2 / CH2Cl2 / 0.5 h
3: 41 percent / K2CO3 / dimethylformamide / 16 h / Ambient temperature
4: 68 percent / ethanol; H2O / 15 h / Ambient temperature
5: 79 percent / conc. HBr / acetic acid / 0.5 h / Ambient temperature
With
thionyl chloride; hydrogen bromide; N-benzyl-trimethylammonium hydroxide; potassium carbonate;
In
methanol; ethanol; dichloromethane; water; acetic acid; N,N-dimethyl-formamide;
DOI:10.1021/jm00398a019