1H-Benz(de)isoquinoline-1,3(2H)-dione, 2-(2-(dimethylamino)ethyl)-

Base Information

Chemical Name:1H-Benz(de)isoquinoline-1,3(2H)-dione, 2-(2-(dimethylamino)ethyl)-
CAS No.:79070-66-9
Molecular Formula:C16H16 N2 O2
Molecular Weight:268.315
Hs Code.:
Mol file:79070-66-9.mol

Synonyms:2-[2-(Dimethylamino)ethyl]-1H-benz[de]isoquinoline-1,3(2H)-dione;2-[2-(dimethylamino)ethyl]-1H-benzo[de]isoquinoline-1,3(2H)-dione;N-[2-(Dimethylamino)ethyl]-1,8-naphthalimide

Suppliers and Price of 1H-Benz(de)isoquinoline-1,3(2H)-dione, 2-(2-(dimethylamino)ethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-(2-(DIMETHYLAMINO)ETHYL)-1H-BENZO[DE]ISOQUINOLINE-1,3(2H)-DIONE 95.00%
5MG
$ 496.01

Total 6 raw suppliers

Chemical Property of 1H-Benz(de)isoquinoline-1,3(2H)-dione, 2-(2-(dimethylamino)ethyl)-

Chemical Property:

Vapor Pressure:1.92E-07mmHg at 25°C
Boiling Point:425.4°C at 760 mmHg
Flash Point:190.2°C
PSA：42.31000
Density:1.25g/cm³
LogP:1.51430

Purity/Quality:

97% ^*data from raw suppliers

2-(2-(DIMETHYLAMINO)ETHYL)-1H-BENZO[DE]ISOQUINOLINE-1,3(2H)-DIONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1H-Benz(de)isoquinoline-1,3(2H)-dione, 2-(2-(dimethylamino)ethyl)-

There total 3 articles about 1H-Benz(de)isoquinoline-1,3(2H)-dione, 2-(2-(dimethylamino)ethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

: 1098129-13-5
5-bromo-2-[2-(dimethylamino)ethyl]-1H-benzo[de]isoquinoline-1,3(2H)-dione

: 98-80-6
phenylboronic acid

: 79070-66-9
2-(2-(dimethylamino)ethyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione

: 5-phenyl-2-[2-(dimethylamino)ethyl]-1H-benzo[de]isoquinoline-1,3(2H)-dione

Guidance literature:: With potassium phosphate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In toluene; for 28h; Reflux; Inert atmosphere;
DOI:10.1016/j.bmc.2010.11.055

Reference yield:

: 81-84-5
1,8-Naphthalic anhydride

: 79070-66-9
2-(2-(dimethylamino)ethyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione

: 5-phenyl-2-[2-(dimethylamino)ethyl]-1H-benzo[de]isoquinoline-1,3(2H)-dione

Guidance literature:: Multi-step reaction with 3 steps

1: bromine; nitric acid / 2 h / 70 °C

2: ethanol / 2 h / Reflux

3: potassium phosphate; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / toluene / 28 h / Reflux; Inert atmosphere

With potassium phosphate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; bromine; nitric acid; In ethanol; toluene; 3: Suzuki-Miyaura cross-coupling;
DOI:10.1016/j.bmc.2010.11.055

Reference yield:

: 24050-49-5
3-bromonaphthalic-1,8-anhydride

: 79070-66-9
2-(2-(dimethylamino)ethyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione

: 5-phenyl-2-[2-(dimethylamino)ethyl]-1H-benzo[de]isoquinoline-1,3(2H)-dione

Guidance literature:: Multi-step reaction with 2 steps

1: ethanol / 2 h / Reflux

2: potassium phosphate; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / toluene / 28 h / Reflux; Inert atmosphere

With potassium phosphate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In ethanol; toluene; 2: Suzuki-Miyaura cross-coupling;
DOI:10.1016/j.bmc.2010.11.055