4-{[12-(Acryloyloxy)dodecyl]oxy}benzoic acid

Base Information

• Chemical Name: 4-{[12-(Acryloyloxy)dodecyl]oxy}benzoic acid
• CAS No.: 112231-57-9
• Molecular Formula: C22H32O5
• Molecular Weight: 376.493
• DSSTox Substance ID: DTXSID10599935
• Nikkaji Number: J3.172.659J
• Wikidata: Q82495897
• Mol file: 112231-57-9.mol

Synonyms:112231-57-9;4-{[12-(Acryloyloxy)dodecyl]oxy}benzoic acid;SCHEMBL9471681;DTXSID10599935;XHRZHMSFJMSPPT-UHFFFAOYSA-N;4-(12-acryloyloxydodecyloxy)benzoic acid

Chemical Property of 4-{[12-(Acryloyloxy)dodecyl]oxy}benzoic acid

Chemical Property:

• XLogP3: 6.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 17
• Exact Mass: 376.22497412
• Heavy Atom Count: 27
• Complexity: 413

Purity/Quality:

99.90% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C=CC(=O)OCCCCCCCCCCCCOC1=CC=C(C=C1)C(=O)O

Technology Process of 4-{[12-(Acryloyloxy)dodecyl]oxy}benzoic acid

There total 5 articles about 4-{[12-(Acryloyloxy)dodecyl]oxy}benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

4-((12-hydroxydodecyl)oxy)benzoic acid (112231-71-7) + acryloyl chloride (814-68-6,25189-84-8) → 4-((12-(acryloyloxy)dodecyl)oxy)benzoic acid (112231-57-9)

Guidance literature:

With N,N-dimethyl acetamide; In 1,4-dioxane; at 0 - 45 ℃; Inert atmosphere;

DOI:10.1039/c5tc00615e

Reference yield: 55.0%

acryloyloxy chloride (1026541-53-6) + 4-((12-hydroxydodecyl)oxy)benzoic acid (112231-71-7) → 4-((12-(acryloyloxy)dodecyl)oxy)benzoic acid (112231-57-9)

Guidance literature:

With N,N-dimethyl-aniline; In 1,4-dioxane; at 20 ℃; for 24h; Inert atmosphere;

DOI:10.1021/ma901960c

Reference yield:

1,12-dodecandiol (5675-51-4) → 4-((12-(acryloyloxy)dodecyl)oxy)benzoic acid (112231-57-9)

Guidance literature:

Multi-step reaction with 4 steps

1.1: hydrogen bromide / toluene / 24 h / 60 °C

2.1: potassium carbonate / acetone / 20 h / Reflux

3.1: potassium hydroxide / ethanol / 16 h / Reflux

3.2: 0.5 h

4.1: N,N-dimethyl-aniline / 1,4-dioxane / 24 h / 20 °C / Inert atmosphere

With hydrogen bromide; potassium carbonate; N,N-dimethyl-aniline; potassium hydroxide; In 1,4-dioxane; ethanol; acetone; toluene;

DOI:10.1021/ma901960c

upstream raw materials:

acryloyloxy chloride

4-((12-hydroxydodecyl)oxy)benzoic acid

1,12-dodecandiol

12-bromododecanol

Downstream raw materials:

C₆₁H₇₂O₁₂