7-Chloro-1-phenyl-1-(trifluoromethyl)-1,2,3,4-tetrahydronaphthalene

Base Information

Chemical Name:7-Chloro-1-phenyl-1-(trifluoromethyl)-1,2,3,4-tetrahydronaphthalene
CAS No.:112298-36-9
Molecular Formula:C17H14ClF3
Molecular Weight:310.746
Hs Code.:
DSSTox Substance ID:DTXSID60555602

Synonyms:7-Chloro-1-phenyl-1-(trifluoromethyl)-1,2,3,4-tetrahydronaphthalene;112298-36-9;SCHEMBL9508313;DTXSID60555602;FPZYOUHBSGXFJO-UHFFFAOYSA-N

Suppliers and Price of 7-Chloro-1-phenyl-1-(trifluoromethyl)-1,2,3,4-tetrahydronaphthalene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 7-Chloro-1-phenyl-1-(trifluoromethyl)-1,2,3,4-tetrahydronaphthalene

Chemical Property:

XLogP3:6.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:310.0736126
Heavy Atom Count:21
Complexity:362

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2=C(C=C(C=C2)Cl)C(C1)(C3=CC=CC=C3)C(F)(F)F

Technology Process of 7-Chloro-1-phenyl-1-(trifluoromethyl)-1,2,3,4-tetrahydronaphthalene

There total 5 articles about 7-Chloro-1-phenyl-1-(trifluoromethyl)-1,2,3,4-tetrahydronaphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 112298-18-7
5-(p-chlorophenyl)-2-phenyl-1,1,1-trifluoropentan-2-ol

: 112298-36-9
7-chloro-1-phenyl-1-(trifluoromethyl)-1,2,3,4-tetrahydronaphthalene

Guidance literature:: With sulfuric acid; trifluoroacetic acid; at 72 ℃; for 1h;
DOI:10.1021/jo00239a010

Reference yield:

: 64473-35-4
3-(4-chlorophenyl)propyl bromide

: 112298-36-9
7-chloro-1-phenyl-1-(trifluoromethyl)-1,2,3,4-tetrahydronaphthalene

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) magnesium / 1.) ether, reflux, 2 h, 2.) a) RT, 1 h, b) reflux, 1 h

2: 60 percent / diethyl ether / 2 h / Heating

3: 90 percent / H₂SO₄, trifluoroacetic acid / 1 h / 72 °C

With sulfuric acid; magnesium; trifluoroacetic acid; In diethyl ether;
DOI:10.1021/jo00239a010

Reference yield:

: phenylmagnesium bromide

: 112298-36-9
7-chloro-1-phenyl-1-(trifluoromethyl)-1,2,3,4-tetrahydronaphthalene

Guidance literature:: Multi-step reaction with 2 steps

1: 60 percent / diethyl ether / 2 h / Heating

2: 90 percent / H₂SO₄, trifluoroacetic acid / 1 h / 72 °C

With sulfuric acid; trifluoroacetic acid; In diethyl ether;
DOI:10.1021/jo00239a010